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本文引用的文献

1
Identification of an H-2Kb-related molecule by molecular cloning.通过分子克隆鉴定一种与H-2Kb相关的分子。
Immunogenetics. 1981;14(5):383-92. doi: 10.1007/BF00373318.
2
A one-step purification of membrane proteins using a high efficiency immunomatrix.使用高效免疫基质一步纯化膜蛋白。
J Biol Chem. 1982 Sep 25;257(18):10766-9.
3
Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes.功能性I类HLA基因HLA - A3的完整核苷酸序列:对HLA基因进化的启示
EMBO J. 1984 Apr;3(4):887-94. doi: 10.1002/j.1460-2075.1984.tb01901.x.
4
Identification of class I major histocompatibility complex encoded molecules in the amphibian Xenopus.在两栖动物非洲爪蟾中鉴定I类主要组织相容性复合体编码分子。
Immunogenetics. 1984;20(4):433-42. doi: 10.1007/BF00345617.
5
Structure of the murine immune response I-A beta locus: sequence of the I-A beta gene and an adjacent beta-chain second domain exon.小鼠免疫反应I-Aβ基因座的结构:I-Aβ基因及相邻β链第二结构域外显子的序列
Cell. 1983 Aug;34(1):179-88. doi: 10.1016/0092-8674(83)90148-4.
6
The murine E alpha immune response gene.小鼠Eα免疫反应基因。
Cell. 1983 Mar;32(3):745-54. doi: 10.1016/0092-8674(83)90060-0.
7
Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex.小鼠主要组织相容性复合体Eβ链和基因的完整一级结构
Proc Natl Acad Sci U S A. 1983 Sep;80(18):5520-4. doi: 10.1073/pnas.80.18.5520.
8
Regions of allelic hypervariability in the murine A alpha immune response gene.小鼠Aα免疫反应基因中的等位基因高变区。
Cell. 1983 Aug;34(1):169-77. doi: 10.1016/0092-8674(83)90147-2.
9
A cDNA clone containing the entire coding sequence of a mouse H-2Kd histocompatibility antigen.一个包含小鼠H-2Kd组织相容性抗原完整编码序列的cDNA克隆。
Nucleic Acids Res. 1983 Mar 11;11(5):1567-77. doi: 10.1093/nar/11.5.1567.
10
Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta.人类主要组织相容性复合体基因DC-3β的克隆与序列分析
Proc Natl Acad Sci U S A. 1984 Aug;81(16):5199-203. doi: 10.1073/pnas.81.16.5199.

主要组织相容性复合体的进化:从两栖动物非洲爪蟾中克隆主要组织相容性复合体I类分子

Evolution of the major histocompatibility complex: molecular cloning of major histocompatibility complex class I from the amphibian Xenopus.

作者信息

Flajnik M F, Canel C, Kramer J, Kasahara M

机构信息

Department of Microbiology and Immunology, University of Miami, FL 33101.

出版信息

Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):537-41. doi: 10.1073/pnas.88.2.537.

DOI:10.1073/pnas.88.2.537
PMID:1703301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC50846/
Abstract

Class I major histocompatibility complex (MHC) cDNA clones have been isolated from an expression library derived from mRNA of an MHC homozygous Xenopus laevis. The nucleotide and predicted amino acid sequences show definite similarity to MHC class I molecules of higher vertebrates. The immunoglobulin-like alpha-3 domain is more similar to the immunoglobulin-like domains of mammalian class II beta chains than to those of mammalian class I molecules, and a tree based on nucleotide sequences of representative MHC genes is presented.

摘要

I类主要组织相容性复合体(MHC)cDNA克隆已从源自MHC纯合非洲爪蟾mRNA的表达文库中分离出来。核苷酸和预测的氨基酸序列与高等脊椎动物的MHC I类分子显示出明确的相似性。免疫球蛋白样α-3结构域与哺乳动物II类β链的免疫球蛋白样结构域比与哺乳动物I类分子的更相似,并给出了基于代表性MHC基因核苷酸序列的系统树。