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[热疗作为治疗前列腺腺瘤的一种方法]

[Hyperthermia as a method for treating prostatic adenoma].

作者信息

Trapeznikova M F, Goldobenko G V, Odinokova V A, Tkachev S I, Bazaev V V, Urenkov S B

出版信息

Urol Nefrol (Mosk). 1990 Jul-Aug(4):31-5.

PMID:1703365
Abstract

Local microwave hyperthermia was used in 15 patients aged 60 to 76 years with prostatic adenoma on an inpatient (n = 8) and outpatient (n = 7) basis. Severe clinical symptoms of prostatic adenoma was considered indication and urinary and prostatic stones were contraindications. Every patient received 6 hyperthermia treatments (41 to 42 degrees C) with a 915 or 460 MHz device. Adenoma of the prostate was treated twice a week. An interval of 3-4 days was used to avoid thermic tolerance. The treatments were well tolerated. Prostatic size was reduced by 15.2 cm2 in 11 patients and unchanged in 1 patient. Three patients required surgery 2 weeks after treatment withdrawal because of adenoma distension with residual urine and 3 patients were operated on for cystostomes. The overall effect of microwave hyperthermia on prostatic adenoma was induction of focal sclerosis in adenoma. This treatment improved uroflowmetric findings and abolished residual urine. Hyperthermia is a reasonably safe conservative option for inoperable patients with prostatic adenoma.

摘要

对15例年龄在60至76岁的前列腺腺瘤患者进行了局部微波热疗,其中8例为住院患者,7例为门诊患者。前列腺腺瘤的严重临床症状被视为适应症,尿路和前列腺结石为禁忌症。每位患者使用915或460兆赫的设备接受6次热疗(41至42摄氏度)。前列腺腺瘤每周治疗两次。间隔3至4天以避免热耐受。治疗耐受性良好。11例患者前列腺体积减小15.2平方厘米,1例患者前列腺体积无变化。3例患者在停止治疗2周后因腺瘤扩张伴残余尿而需要手术,3例患者因膀胱造口术接受手术。微波热疗对前列腺腺瘤的总体作用是诱导腺瘤局灶性硬化。该治疗改善了尿流率检查结果并消除了残余尿。对于无法手术的前列腺腺瘤患者,热疗是一种相当安全的保守选择。

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