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Stepped care vs. matched care for mood and anxiety disorders: a randomized trial in routine practice.阶梯式护理与匹配护理治疗情绪和焦虑障碍：一项常规实践中的随机试验
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Patterns of mean-level change in personality traits across the life course: a meta-analysis of longitudinal studies.人生历程中人格特质平均水平变化模式：纵向研究的荟萃分析
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Determinants of subjective quality of life in depressed patients: the role of self-esteem, response styles, and social support.抑郁症患者主观生活质量的决定因素：自尊、应对方式及社会支持的作用。
J Affect Disord. 2005 Jun;86(2-3):205-13. doi: 10.1016/j.jad.2005.01.014.
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Minor depression: risk profiles, functional disability, health care use and risk of developing major depression.轻度抑郁症：风险概况、功能残疾、医疗保健利用情况以及发展为重度抑郁症的风险。
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Affective disorders, personality and personality disorders.
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Personality and depressive symptoms: a multi-dimensional analysis.人格与抑郁症状：多维分析
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Use of the five-factory inventory in characterizing patients with major depressive disorder.使用五厂库存来表征重度抑郁症患者。
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情绪和焦虑障碍患者的人格特质与健康相关生活质量

Personality traits and health-related quality of life in patients with mood and anxiety disorders.

作者信息

van Straten Annemieke, Cuijpers Pim, van Zuuren Florence J, Smits Niels, Donker Marianne

机构信息

Department of Clinical Psychology, Faculty FPP, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands.

出版信息

Qual Life Res. 2007 Feb;16(1):1-8. doi: 10.1007/s11136-006-9124-x. Epub 2006 Oct 11.

DOI:10.1007/s11136-006-9124-x
PMID:17033892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2778691/
Abstract

BACKGROUND

Health-related quality of life (HRQL) is an accepted outcome measure in patients with mood and anxiety disorders. Yet, surprisingly little attention has been paid to the determinants. In this paper we test the hypothesis that it is associated with personality traits while controlling for mental disorders.

METHODS

A large sample of outpatients (n = 640) with mood and anxiety disorders was studied. The empirically supported five factor model of normal personality traits was assessed using the NEO-FFI and includes: neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness. Mental disorders were assessed with the CIDI, and HRQL with the SF-36.

RESULTS

Regression analyses revealed that the NEO-FFI scores, with the exception of conscientiousness, were significantly associated with SF-36 subscales and summary scores, independently from the mental disorders. The percentage of explained variance due to the personality traits was highest for the subscales Vitality (10.0%), Mental Health (13.3%) and the Mental Health Summary Score (9.5%). Furthermore, specific personality traits were related to specific SF-36 subscales.

CONCLUSIONS

A low HRQL of patients with mood or anxiety disorders is not only determined by the disease or the current health but is also shaped by personality traits that are relatively stable throughout an individual's life time.

摘要

背景

健康相关生活质量（HRQL）是心境障碍和焦虑症患者公认的结局指标。然而，令人惊讶的是，人们对其决定因素关注甚少。在本文中，我们检验这样一个假设，即在控制精神障碍的同时，它与人格特质相关。

方法

对一大样本（n = 640）患有心境障碍和焦虑症的门诊患者进行研究。使用NEO-FFI评估经验证支持的正常人格特质五因素模型，该模型包括：神经质、外向性、开放性、宜人性和尽责性。使用CIDI评估精神障碍，使用SF-36评估HRQL。

结果

回归分析显示，除尽责性外，NEO-FFI得分与SF-36分量表及总分显著相关，且独立于精神障碍。人格特质导致的方差解释百分比在活力分量表（10.0%）、心理健康分量表（13.3%）和心理健康总分（9.5%）中最高。此外，特定的人格特质与特定的SF-36分量表相关。

结论

心境障碍或焦虑症患者的低HRQL不仅由疾病或当前健康状况决定，还受到个体一生中相对稳定的人格特质的影响。