Hagiuda Jun, Ueno Munehisa, Ashimine Satoshi, Kuroda Isao, Ishizawa Keisuke, Deguchi Nobuhiro
Department of Urology, Saitama Medical University, Saitama, Japan.
BMC Urol. 2006 Oct 11;6:28. doi: 10.1186/1471-2490-6-28.
Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs. A few cases of Langerhans cell histiocytosis on the penis have been reported in the literature. We present a case of Langerhans cell histiocytosis on the penis and review the similar cases in the literature.
The patient was a 13-year-old boy who had a history of lymph node, femur bone, and pituitary-thalmic axis lesions from Langerhans cell histiocytosis who noticed a painful nodule on the prepuce of his penis. The histological and immunohistochemical examination fulfilled the criteria of Langerhans cell histiocytosis.
We herein describe the case reported of Langerhans cell histiocytosis on the penis.
朗格汉斯细胞组织细胞增多症主要影响幼儿,其特征是CD1a+树突状朗格汉斯细胞在骨骼、皮肤和其他器官中积聚。文献中已报道了少数阴茎朗格汉斯细胞组织细胞增多症病例。我们报告一例阴茎朗格汉斯细胞组织细胞增多症病例,并回顾文献中的类似病例。
该患者为一名13岁男孩,有朗格汉斯细胞组织细胞增多症导致的淋巴结、股骨和垂体-丘脑轴病变史,他注意到阴茎包皮上有一个疼痛性结节。组织学和免疫组化检查符合朗格汉斯细胞组织细胞增多症的标准。
我们在此描述了阴茎朗格汉斯细胞组织细胞增多症的报告病例。