Vasios Christos E, Angelone Leonardo M, Purdon Patrick L, Ahveninen Jyrki, Belliveau John W, Bonmassar Giorgio
Harvard Medical School, Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Building 149, 13th Street, Charlestown 02129, USA.
Neuroimage. 2006 Dec;33(4):1082-92. doi: 10.1016/j.neuroimage.2006.07.038. Epub 2006 Oct 10.
We aimed at improving the signal-to-noise ratio (SNR) of electroencephalography (EEG) during magnetic resonance imaging (MRI) by introducing a new EEG cap ("InkCap") based on conductive ink technology. The InkCap was tested with temperature measurements on an electrically conductive phantom head and during structural and functional MRI (fMRI) recordings in 11 healthy human volunteers at 7 T. Combined EEG/fMRI measurements were conducted to study the interaction between the two modalities. The EEG recordings with the InkCap demonstrated up to a five-fold average decrease in signal variance during echo-planar imaging, with respect to a cap made of standard carbon fiber leads. During concurrent EEG/fMRI measurements in human volunteers, alpha oscillations were clearly detected at 7 T. Minimal artifacts were present in the T2* and high-resolution structural MR images of the brain parenchyma. Our results show that the InkCap technology considerably improves the quality of both EEG and (f)MRI during concurrent measurements even at 7 T.
我们旨在通过引入一种基于导电墨水技术的新型脑电图(EEG)帽(“InkCap”)来提高磁共振成像(MRI)期间脑电图的信噪比(SNR)。在一个导电的模拟头部上进行了温度测量,并在7T场强下对11名健康人类志愿者进行了结构和功能磁共振成像(fMRI)记录,以此对InkCap进行测试。同时进行脑电图/功能磁共振成像测量以研究这两种模式之间的相互作用。与由标准碳纤维导联制成的帽相比,使用InkCap进行的脑电图记录显示,在回波平面成像期间信号方差平均降低了五倍。在人类志愿者同时进行脑电图/功能磁共振成像测量期间,在7T场强下清晰地检测到了阿尔法振荡。脑实质的T2*和高分辨率结构磁共振图像中存在的伪影极少。我们的结果表明,即使在7T场强下,InkCap技术在同时测量期间也能显著提高脑电图和(功能)磁共振成像的质量。