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应对动态生物膜的复杂性。

Managing the complexity of a dynamic biofilm.

作者信息

Thomas John G, Nakaishi Lindsay A

机构信息

Department of Pathology, West Virginia University, School of Medicine, Morgantown, USA.

出版信息

J Am Dent Assoc. 2006 Nov;137 Suppl:10S-15S. doi: 10.14219/jada.archive.2006.0409.

DOI:10.14219/jada.archive.2006.0409
PMID:17035670
Abstract

BACKGROUND

This article provides an overview of the history of oral microbiology, a discussion of dental plaque as both a microbial community and a biofilm, and a review of the measures available to control the oral microflora.

TYPES OF STUDIES REVIEWED

The authors reviewed the literature related to oral microbiology and associated infectious diseases. They also examined articles that detailed the structure and physiology of biofilms, including dental plaque biofilms.

CONCLUSIONS

Biofilms cannot be eliminated. The pathogenic nature of the dental plaque biofilm can be diminished in the oral cavity by reducing the bioburden and effectively maintaining a normal oral flora via oral hygiene procedures that include daily toothbrushing, flossing and rinsing with an antimicrobial mouthrinse. An oral hygiene regimen that includes rinsing with an antimicrobial mouthrinse is a practical approach to the prevention and management of periodontal diseases. This strategy may have wider benefits when the link between periodontal disease and certain systemic diseases is considered.

CLINICAL IMPLICATIONS

An effective oral hygiene regimen can help control dental plaque biofilm and associated periodontal diseases.

摘要

背景

本文概述了口腔微生物学的历史,讨论了作为微生物群落和生物膜的牙菌斑,并综述了控制口腔微生物群的可用措施。

综述的研究类型

作者回顾了与口腔微生物学及相关传染病有关的文献。他们还查阅了详细阐述生物膜(包括牙菌斑生物膜)结构和生理学的文章。

结论

生物膜无法被消除。通过减少生物负荷并通过包括每日刷牙、使用牙线和用抗菌漱口水漱口在内的口腔卫生程序有效维持正常口腔菌群,可以减轻口腔中牙菌斑生物膜的致病性质。包括用抗菌漱口水漱口在内的口腔卫生方案是预防和管理牙周疾病的实用方法。当考虑到牙周疾病与某些全身性疾病之间的联系时,这一策略可能具有更广泛的益处。

临床意义

有效的口腔卫生方案有助于控制牙菌斑生物膜及相关的牙周疾病。

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Managing the complexity of a dynamic biofilm.应对动态生物膜的复杂性。
J Am Dent Assoc. 2006 Nov;137 Suppl:10S-15S. doi: 10.14219/jada.archive.2006.0409.
2
Antimicrobial mouthrinses and the management of periodontal diseases. Introduction to the supplement.抗菌漱口水与牙周疾病的管理。增刊引言。
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The rationale for the daily use of an antimicrobial mouthrinse.每日使用抗菌漱口水的基本原理。
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Intermicrobial Interactions as a Driver for Community Composition and Stratification of Oral Biofilms.微生物间相互作用作为口腔生物膜群落组成和分层的驱动因素。
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J Am Dent Assoc. 2008 Sep;139(9):1182-90. doi: 10.14219/jada.archive.2008.0333.

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