Plouffe J F, File T M
Ohio State University Medical Center, Division of Infectious Diseases, Department of Internal Medicine, Columbus, OH 43210, USA.
Curr Opin Infect Dis. 1999 Apr;12(2):127-32. doi: 10.1097/00001432-199904000-00004.
Legionella spp. are significant causes of both community-acquired pneumonia and nosocomial pneumonia. More than 40 species of Legionella have now been identified. The spectrum of disease ranges from asymptomatic infection to serious disease, with two specific syndromes identified: Legionnaire's disease and Pontiac fever. Hospital-acquired infection arises from the presence of Legionella in the hospital water supply. The optimal approach for the detection and prevention of nosocomial infection is debatable-whether or not periodic sampling of hospital water systems should be carried out in the absence of clinical cases is controversial. Newer macrolides or newer fluoroquinolone agents are the preferred therapy for serious diseases caused by Legionella.
军团菌属是社区获得性肺炎和医院获得性肺炎的重要病因。现已鉴定出40多种军团菌。疾病谱范围从无症状感染到严重疾病，已确定两种特定综合征：军团病和庞蒂亚克热。医院获得性感染源于医院供水系统中存在军团菌。对于医院获得性感染的检测和预防的最佳方法存在争议——在无临床病例的情况下是否应定期对医院水系统进行采样存在争议。新型大环内酯类药物或新型氟喹诺酮类药物是治疗由军团菌引起的严重疾病的首选疗法。
