伊拉克地中海贫血患儿中丙型肝炎病毒特异性抗体的血清流行率。
Seroprevalence of hepatitis C virus specific antibodies among Iraqi children with thalassaemia.
作者信息
Al-Kubaisy W A, Al-Naib K T, Habib M
机构信息
Department of Community Medicine, Al-Nahrain University College of Medicine, Baghdad, Iraq.
出版信息
East Mediterr Health J. 2006 Jan-Mar;12(1-2):204-10.
The seroprevalence of hepatitis C virus (HCV) specific antibodies and HCV genotypes distribution were studied among 559 Iraqi children with thalassaemia in receipt of repeated blood transfusions. HCV-specific antibodies were detected in 376 (67.3%) serum samples using third-generation enzyme immunoassay and confirmatory immunoblot assays. Of 78 randomly selected sera, 48 (61.5%) were HCV-RNA positive. HCV genotypes 1a, 1b, 4 and mixed 1b and 4 were demonstrated in 13 (27.1%), 11 (22.9%), 17 (35.4%) and 7 (14.6%) sera respectively. Strict measures for the controlling the spread of HCV are needed by introducing advanced techniques for blood donor screening.
在559名接受反复输血的伊拉克地中海贫血儿童中，研究了丙型肝炎病毒（HCV）特异性抗体的血清流行率和HCV基因型分布。使用第三代酶免疫测定和确证免疫印迹测定法在376份（67.3%）血清样本中检测到HCV特异性抗体。在随机选择的78份血清中，48份（61.5%）HCV-RNA呈阳性。分别在13份（27.1%）、11份（22.9%）、17份（35.4%）和7份（14.6%）血清中检测到HCV基因型1a、1b、4以及混合的1b和4型。需要通过引入先进的献血者筛查技术来采取严格措施控制HCV的传播。
Zotero 插件