Duval K, Marceau P, Pérusse L, Lacasse Y
Research Center, Laval Hospital, Institute of Cardiology and Pneumology of Laval University, Quebec, Canada.
Obes Rev. 2006 Nov;7(4):347-60. doi: 10.1111/j.1467-789X.2006.00244.x.
The measurement of quality of life in patients with obesity is useful to evaluate the effects of treatment (including bariatric surgery) and may influence the development of clinical pathways, service provision, healthcare expenditures and public health policy. Consequently, clinicians, researchers and policy makers must rely on valid measurement instruments. We reviewed 11 obesity-specific quality of life questionnaires and classified them according to their domain of interest and described their measurement properties (specifications, validity, reliability, responsiveness and interpretability). We found that (i) nine questionnaires were developed specifically to be used as evaluative instruments in clinical trials; (ii) only three targeted populations with morbid obesity (body mass index > 40 kg m(-2)); (iii) construct validity was properly studied in three questionnaires; (iv) demonstration of responsiveness from independent randomized controlled trials was available for two of the 11 questionnaires; (v) keys to interpretation of scores were provided for three questionnaires. Future research should include further validation and a better definition of the interpretability of existing instruments.
对肥胖患者生活质量的测量有助于评估治疗效果（包括减肥手术），并可能影响临床路径的制定、服务提供、医疗保健支出和公共卫生政策。因此，临床医生、研究人员和政策制定者必须依赖有效的测量工具。我们回顾了11份针对肥胖症的生活质量问卷，并根据其感兴趣的领域对它们进行了分类，描述了它们的测量特性（规格、效度、信度、反应度和可解释性）。我们发现：（i）9份问卷是专门为在临床试验中用作评估工具而开发的；（ii）只有3份问卷针对患有病态肥胖（体重指数>40 kg/m²）的人群；（iii）在3份问卷中对结构效度进行了恰当的研究；（iv）11份问卷中有2份可从独立随机对照试验中获得反应度的证明；（v）3份问卷提供了分数解释的关键。未来的研究应包括对现有工具进行进一步验证，并更好地定义其可解释性。
