超越菌株分型和分子流行病学：传染病的综合遗传流行病学

Beyond strain typing and molecular epidemiology: integrated genetic epidemiology of infectious diseases.

作者信息

Tibayrenc M

机构信息

Centre d'Etudes sur le Polymorphisme des Microorganismes (CEPM), UMR CNRS/ORSTOM 9926, ORSTOM, BP 5045, 34032 Montpellier Cedex 1, France.

出版信息

Parasitol Today. 1998 Aug;14(8):323-9. doi: 10.1016/s0169-4758(98)01286-1.

DOI:10.1016/s0169-4758(98)01286-1

PMID:17040799

Abstract

In the past 20 years, genetic and molecular methods for characterizing pathogen strains have taken a major place in modern approaches to epidemiology of parasitic and other infectious diseases. Here, Michel Tibayrenc explains the main concepts used in this field of research, with special emphasis on the approaches developed in his team, and suggests future avenues to explore.

摘要

在过去20年里，用于鉴定病原体菌株的遗传和分子方法在现代寄生虫病及其他传染病流行病学研究方法中占据了重要地位。在此，米歇尔·蒂巴伦茨解释了该研究领域中使用的主要概念，特别强调了其团队所开发的方法，并提出了未来有待探索的方向。