Corless I B, Nicholas P K, Wantland D, McInerney P, Ncama B, Bhengu B, McGibbon C, Davis S
Massachusetts General Hospital Institute of Health Professions, Boston, Massachusetts 02129, USA.
Int J Tuberc Lung Dis. 2006 Oct;10(10):1159-65.
Out-patient tuberculosis (TB) clinics in Durban, South Africa.
Health care provider concerns about persons with active TB defaulting on medications led to a study of adherence among persons receiving anti-tuberculosis therapy and, specifically, the relationships between meaning in life, life goals, sense of coherence, social support, symptom presence and intensity, and adherence in individuals diagnosed with TB.
A cross-sectional, descriptive design was used to gather self-reported data from TB-infected individuals who were enrolled in out-patient clinics. Data were collected from 159 Zulu and/or English-speaking persons who agreed to participate in the study.
A significant relationship was found between higher life goals and adherence to TB treatment (P = 0.027). Analysis of variance revealed that higher meaning in life ratings were significantly associated with older age (P = 0.007). Having children and children living in the same household were significantly associated with low meaning in life ratings (P = 0.006 and P < or = 0.001, respectively), indicating that these individuals were more concerned about basic matters of home and sustenance.
The results of this study indicate that meaning in life and life goals may be useful for identifying individuals who will require additional support in adhering to anti-tuberculosis treatment.
南非德班的门诊结核病诊所。
医疗服务提供者对活动性结核病患者不按时服药的担忧，促使开展了一项关于接受抗结核治疗患者依从性的研究，特别是关于确诊为结核病的个体的生活意义、生活目标、连贯感、社会支持、症状的存在与强度以及依从性之间的关系。
采用横断面描述性设计，从门诊诊所登记的结核病感染个体中收集自我报告数据。从159名同意参与研究的祖鲁语和/或英语使用者中收集数据。
发现较高的生活目标与结核病治疗依从性之间存在显著关系（P = 0.027）。方差分析显示，较高的生活意义评分与年龄较大显著相关（P = 0.007）。有孩子以及孩子与自己同住一个家庭与较低的生活意义评分显著相关（分别为P = 0.006和P≤0.001），这表明这些个体更关注家庭和生计的基本问题。
本研究结果表明，生活意义和生活目标可能有助于识别在坚持抗结核治疗方面需要额外支持的个体。
