Nitzsché R, Gueunoun M, Lamaison D, Lascault G, Pioger G, Richard M, Malherbe O, Limousin M
ELA Médical, Montrouge, France.
Pacing Clin Electrophysiol. 1990 Dec;13(12 Pt 2):1711-8. doi: 10.1111/j.1540-8159.1990.tb06877.x.
Endless-loop tachycardia (ELT) is one of the most common pacemaker mediated tachycardia. An innovative ELT protection algorithm has proven to be clinically effective. A new improved version that will eliminate the need to program any parameter is now under clinical evaluation. Nine patients entered the study: six men and three women, aged 52 +/- 22 years. This automatic algorithm needs only 10 cycles to detect and confirm an ELT. Three hundred thirty-three ELTs lasting more than 9 cycles have been induced and analyzed. The total results are the following: mean duration: 6.7 sec +/- 3.1; mean ELT rate: 137 +/- 21.9 bpm, mean programmed upper rate limit (URL): 142.5 +/- 26.5 bpm (Only 70% of ELTs presented rates equal to programmed URL). (1) ELTs reduced by postventricular atrial refractory period (PVARP) extension on one cycle: 291 ELTs (87%). ELT rate: 128.5 +/- 18.2 bpm. (2) Retrograde block: algorithm operation may induce a retrograde block due to a short atrioventricular delay (AVD) applied during the confirmation phase to discriminate an ELT from a stable sinus rhythm. Thirty-two ELTs (10%) have been reduced and detected on a retrograde block occurrence. (3) Algorithm failure due to an unstable ventriculoatrial conduction time (VACT) even at fixed rate or to a retrograde Wenckebach behavior on AVD reduction during the confirmation phase. A total of 10 algorithms failed to detect or confirm an ELT have been recorded (3%). Mean duration: 8.2 +/- 4.2 sec, mean ELT rate: 148.9 +/- 14.3 bpm. This new fully automatic algorithm has reduced 97% of ELTs, including high rate episodes (100-175 bpm).(ABSTRACT TRUNCATED AT 250 WORDS)
无休止环性心动过速(ELT)是最常见的起搏器介导的心动过速之一。一种创新的ELT保护算法已被证明具有临床有效性。一种新的改进版本即将进行临床评估,该版本将无需对任何参数进行编程。9名患者进入研究:6名男性和3名女性,年龄52±22岁。这种自动算法仅需10个心动周期即可检测并确认ELT。已诱发并分析了333次持续超过9个心动周期的ELT。总体结果如下:平均持续时间:6.7秒±3.1;平均ELT心率:137±21.9次/分钟,平均程控上限频率(URL):142.5±26.5次/分钟(仅70%的ELT心率等于程控URL)。(1)通过延长一个心动周期的心室后心房不应期(PVARP)减少的ELT:291次ELT(87%)。ELT心率:128.5±18.2次/分钟。(2)逆向阻滞:算法操作可能会由于在确认阶段应用短房室延迟(AVD)以区分ELT与稳定窦性心律而诱发逆向阻滞。在发生逆向阻滞时减少并检测到32次ELT(10%)。(3)由于心室心房传导时间(VACT)不稳定(即使在固定心率时)或在确认阶段AVD减小时出现逆向文氏现象导致算法失败。总共记录到10次算法未能检测或确认ELT(3%)。平均持续时间:8.2±4.2秒,平均ELT心率:148.9±14.3次/分钟。这种新的全自动算法减少了97%的ELT,包括高心率发作(100 - 175次/分钟)。(摘要截取自250字)