Rognoni G, Occhetta E, Perucca A, Magnani A, Francalacci G, Audoglio R, Rossi P
Division of Cardiology, Ospedale Maggiore, Novara, Italy.
Pacing Clin Electrophysiol. 1991 Nov;14(11 Pt 2):1828-34. doi: 10.1111/j.1540-8159.1991.tb02774.x.
Endless loop tachycardia (ELT) is a possible complication in dual chamber pacing; it is usually prevented by programming the atrial refractory period (PVARP) longer than the retrograde ventriculoatrial (VA) conduction interval; this in some patients limits the upper rate. In 15 patients with a DDD (nine patients) or a single-pass lead VDD pacemaker (six patients) and retrograde atrial activation, telemetric recording documented a significant difference in amplitude of antegrade, and retrograde atrial potentials (VDD 1.21 +/- 0.32 mV vs 0.56 +/- 0.23 mV, P = 0.008; DDD 2.7 +/- 1 vs 1.8 +/- 1 mV, P = 0.038; Student's t-test for paired data). In 3/15 patients ELT stopped after programming of atrial sensitivity to a value greater than the retrograde P wave amplitude; in 11/15 patients this occurred at a sensing value lower than or equal to retrograde P wave amplitude with a high pass band filter operating. One patient required PVARP lengthening. Holter monitoring showed no more ELTs. In most patients with a DDD or single-pass lead VDD pacemaker with widely programmable sensing amplitude and Hi/Low bandpass filters, individual programming of atrial channel sensitivity prevents ELT without affecting the PVARP and, consequently, upper rate limit.
无休止环形心动过速(ELT)是双腔起搏可能出现的并发症;通常通过将心房不应期(PVARP)程控得长于逆向心室心房(VA)传导间期来预防;这在一些患者中限制了上限频率。在15例植入DDD起搏器(9例)或单极导线VDD起搏器(6例)且有逆向心房激动的患者中,遥测记录显示顺向和逆向心房电位幅度存在显著差异(VDD起搏器:1.21±0.32 mV对0.56±0.23 mV,P = 0.008;DDD起搏器:2.7±1 mV对1.8±1 mV,P = 0.038;配对数据的学生t检验)。在15例患者中的3例中,将心房感知灵敏度程控到大于逆向P波幅度的值后,ELT终止;在15例患者中的11例中,在高通带滤波器工作的情况下,在低于或等于逆向P波幅度的感知值时发生了这种情况。1例患者需要延长PVARP。动态心电图监测显示未再出现ELT。对于大多数植入DDD或单极导线VDD起搏器且感知幅度和高低通带滤波器可广泛程控的患者,对心房通道灵敏度进行个体化程控可预防ELT,而不影响PVARP,因此也不影响上限频率。