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超声衰减对声镊可行性的影响。

Effect of ultrasonic attenuation on the feasibility of acoustic tweezers.

作者信息

Lee Jungwoo, Shung K Kirk

机构信息

Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.

出版信息

Ultrasound Med Biol. 2006 Oct;32(10):1575-83. doi: 10.1016/j.ultrasmedbio.2006.05.021.

Abstract

A modified mathematical formulation for the calculation of axial radiation force was developed to incorporate the effect of ultrasonic attenuation. Axial forces, Fresnel coefficients, average internal attenuation factors and effective internal reflection coefficients were calculated. Thermal and mechanical indices were also computed to address the safety issues in the implementation of acoustic tweezers and were found to be negligible. The results show that the overall distribution of axial forces is barely affected by attenuation. Furthermore, it is found that attenuation actually works against the scattering force and may therefore reinforce the axial trapping force. For a particle size of 180 microm, the maximum trapping force increases from 29.8 x 10(-11) N to 30.3 x 10(-11) N by 1.7% when attenuation is included. In light of these results, it appears that acoustic tweezers may still be feasible beyond the focal point even under the influence of attenuation.

摘要

为了纳入超声衰减的影响,开发了一种用于计算轴向辐射力的改进数学公式。计算了轴向力、菲涅耳系数、平均内部衰减因子和有效内部反射系数。还计算了热指数和机械指数,以解决声镊实施中的安全问题,发现这些指数可以忽略不计。结果表明,轴向力的总体分布几乎不受衰减影响。此外,发现衰减实际上与散射力相反,因此可能会增强轴向捕获力。对于粒径为180微米的粒子,当考虑衰减时,最大捕获力从29.8×10⁻¹¹牛增加到30.3×10⁻¹¹牛,增加了1.7%。鉴于这些结果,似乎即使在衰减的影响下,声镊在焦点之外仍可能是可行的。

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