Lu Fang, Lin Wen-han
State Key laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.
Zhongguo Zhong Yao Za Zhi. 2006 Jun;31(11):894-8.
To study the chemical constituents of the marine sponge Rhabdastrella aff. distincta.
Compounds were obtained by normal phase silica gel, Sephadex LH-20, reverse phase chromatogrophy and methylation method. These structures were determined on the basis of IR, MS, NMR spectral analysis.
Eight compounds were isolated from bioactive CH3Cl fraction and identified as geoditin A (1), geoditin B (2), stellettin A (5), stellettin B (4), stellettin C (3), stellettinE (7), rhabdastrellic acid A (8) and the methyl ester of stellettin E (6).
All these compounds were obtained from this species for the first time.
研究海洋海绵近似独特横纹海绵（Rhabdastrella aff. distincta）的化学成分。
通过正相硅胶、葡聚糖凝胶LH-20、反相色谱法和甲基化方法获得化合物。基于红外光谱（IR）、质谱（MS）、核磁共振光谱（NMR）分析确定这些结构。
从生物活性氯甲烷馏分中分离出8种化合物，鉴定为地地汀A（1）、地地汀B（2）、斯氏海绵素A（5）、斯氏海绵素B（4）、斯氏海绵素C（3）、斯氏海绵素E（7）、横纹海绵酸A（8）和斯氏海绵素E甲酯（6）。
所有这些化合物均首次从该物种中获得。
