Kamitani Kazuo, Yoshida Hitoshi, Takagi Mari, Minami Masami, Tokutake Miki, Kishi Riho, Horikawa Hideyo, Higuchi Akiko
Department of Anesthesia, Toyama Prefectural Central Hospital, Toyama 930-8550.
Masui. 2006 Oct;55(10):1216-21.
Amino acid infusion prevents intraoperative hypothermia. The purpose of this study is to examine the effect of amino acid infusion on intraoperative core temperature of patients during laparotomy.
Forty-two patients (duration of surgery of 180 min or more) and 32 patients (duration of surgery less than 180 min) scheduled for open gastrectomy under sevoflurane anesthesia combined with epidural anesthesia were randomly allocated to receive either amino acid solution (A group) or electrolyte solution (S group) intravenously. Each solution was started at anesthesia induction. The levels of tympanic temperature were recorded after induction, during surgery and at extubation.
Patients in each of the two groups (A group vs. S group) were comparable with their characteristics and anesthetic management. Amino acid infusion prevented intraoperative hypothermia for cases of 180 min or more. The number of patients with temperature of less than 35.5 degrees C in A group was less those that in S group for cases shorter than 180 min.
Amino acid infusion has more preventive effect on intraoperative hypothermia than electrolyte solution.
输注氨基酸可预防术中体温过低。本研究旨在探讨输注氨基酸对开腹手术患者术中核心体温的影响。
将计划在七氟醚麻醉联合硬膜外麻醉下行开腹胃切除术的42例患者（手术时长180分钟或更长）和32例患者（手术时长少于180分钟）随机分为两组，分别静脉输注氨基酸溶液（A组）或电解质溶液（S组）。每种溶液均在麻醉诱导时开始输注。记录诱导后、手术期间及拔管时的鼓膜温度水平。
两组患者（A组与S组）的特征及麻醉管理情况具有可比性。对于手术时长180分钟或更长的病例，输注氨基酸可预防术中体温过低。对于手术时长少于180分钟的病例，A组体温低于35.5摄氏度的患者数量少于S组。
与电解质溶液相比，输注氨基酸对术中体温过低具有更强的预防作用。
