Ohe Yoko, Kunimasa Kenya, Watanabe Yoshio
Masui. 2014 Jun;63(6):623-8.
Amino acid infusion was reported to be effective in preventing hypothermia during surgery. We investigated whether the antihypothermic effects of amino acid infusion depend on the anesthetic agent used for surgery.
Patients underwent abdominal surgery lasting at least 2 hours under general anesthesia combined with epidural anesthesia Patients were divided into 4 groups depending on the anesthetic agents sevoflurane (S) or propofol (P) and on receiving amino acid infusion (A) or not (NA). Amino acid preparation 10% was infused for approximately 2 hours, starting when the patient entered the operating room. Pharyngeal temperature and palm temperature were measured every 5 minutes.
Pharyngeal temperature was significantly higher (P < 0.001) at 60 minutes and later among patients receiving amino acid infusion in both SA and PA groups but did not differ between SA and PA groups. Palm temperature was also higher after amino acid infusion in the SA and PA, but was significantly higher in P as compared with S (A : P = 0.014; NA : P < 0.001).
Core and peripheral temperatures increased after amino acid infusion in patients receiving sevoflurane or propofol. Our results suggest that the antihypothermic effects of amino acid infusion do not depend on the anesthetic used.
据报道，输注氨基酸在预防手术期间体温过低方面有效。我们研究了输注氨基酸的抗体温过低作用是否取决于手术中使用的麻醉剂。
患者在全身麻醉联合硬膜外麻醉下接受至少持续2小时的腹部手术。根据麻醉剂七氟醚（S）或丙泊酚（P）以及是否接受氨基酸输注（A）或不接受（NA），将患者分为4组。10%的氨基酸制剂从患者进入手术室开始输注约2小时。每5分钟测量一次咽部温度和手掌温度。
SA组和PA组中接受氨基酸输注的患者在60分钟及以后咽部温度显著更高（P < 0.001），但SA组和PA组之间无差异。SA组和PA组在输注氨基酸后手掌温度也更高，但与S相比，P组显著更高（A组：P = 0.014；NA组：P < 0.001）。
接受七氟醚或丙泊酚的患者在输注氨基酸后核心温度和外周温度升高。我们的结果表明，输注氨基酸的抗体温过低作用不取决于所使用的麻醉剂。
