Kamitani Kazuo, Higuchi Akiko, Nohara Akemi, Takagi Mari, Tokutake Miki, Horikawa Hideyo, Yoshida Hitoshi, Asahi Takehisa
Department of Anesthesia, Toyama Prefectural Central Hospital, Toyama 930-8550.
Masui. 2005 Nov;54(11):1258-62.
Propofol anesthesia has more thermogenic effect than isoflurane when combined with amino acid solutions. The purpose of this study is to compare the effects of intraoperative administration of amino acid solutions on intraoperative core temperature under propofol anesthesia with those under sevoflurane anesthesia.
Thirty patients scheduled for total hip arthroplasty were randomly allocated to undergo either propofol anesthesia or sevoflurane anesthesia. i.v. amino acid infusion started at anesthesia induction in all patients. The values of tympanic temperature were recorded after induction, during surgery and at extubation.
Patients in the two groups were comparable with their characteristics and anesthetic managements. The temperatures under sevoflurane anesthesia were unchanged during study, whereas those under propofol anesthesia decreased significantly.
Sevoflurane anesthesia has more preventive effect on intraoperative hypothermia than propofol anesthesia when combined with amino acid solutions.
丙泊酚麻醉与氨基酸溶液合用时比异氟烷具有更强的产热效应。本研究旨在比较术中给予氨基酸溶液对丙泊酚麻醉和七氟烷麻醉下术中核心体温的影响。
30例计划行全髋关节置换术的患者被随机分配接受丙泊酚麻醉或七氟烷麻醉。所有患者在麻醉诱导时开始静脉输注氨基酸。诱导后、手术期间和拔管时记录鼓膜温度值。
两组患者的特征和麻醉管理具有可比性。七氟烷麻醉下的体温在研究期间无变化,而丙泊酚麻醉下的体温显著下降。
当与氨基酸溶液合用时,七氟烷麻醉比丙泊酚麻醉对术中体温过低具有更强的预防作用。