Peinemann F, Cooper D N, Grzeschik K H, Schmidtke J
Institut für Humangenetik der Universität, Göttingen, Federal Republic of Germany.
Hum Genet. 1991 Feb;86(4):394-7. doi: 10.1007/BF00201842.
pJU78 is a 2.9-kb cloned human DNA segment derived from Xq24-q26. When used as a hybridization probe, it detects some 25 related sequences dispersed over the genome, including several autosomes and the X and Y chromosomes. Several pJU78-related sequences were chromosomally allocated and five different restriction fragment length polymorphisms detected and partially characterized in population and family studies. This sequence family was not found in non-primate species. The sequence appears to lack CpG-island character and is not detectably expressed in a variety of human tissues.
pJU78是一个源自Xq24 - q26的2.9千碱基对的克隆人类DNA片段。当用作杂交探针时,它能检测到约25个分散在基因组中的相关序列,包括几条常染色体以及X和Y染色体。几个与pJU78相关的序列已进行染色体定位,并且在群体和家系研究中检测到了五种不同的限制性片段长度多态性并对其进行了部分特征描述。在非灵长类物种中未发现这个序列家族。该序列似乎缺乏CpG岛特征,并且在多种人类组织中未检测到明显表达。