F1组蛋白与超螺旋DNA的相互作用。
Interaction of f1 histone with superhelical DNA.
作者信息
Vogel T, Singer M F
出版信息
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2597-600. doi: 10.1073/pnas.72.7.2597.
Abstract
The superhelicity of double-stranded, closed circular SV40 DNA was altered by the addition of various amounts of ethidium bromide. The interaction of f1 histone with the series of molecules of various superhelicities was studied. The extent of interaction increases with increasing superhelicity regardless of whether it is of the positive or negative sense. The interaction of f1 histone with superhelical DNA is shown to be reversible.
摘要
通过添加不同量的溴化乙锭改变双链闭环SV40 DNA的超螺旋状态。研究了f1组蛋白与一系列具有不同超螺旋状态分子的相互作用。无论超螺旋是正还是负，相互作用的程度都随超螺旋度的增加而增加。结果表明，f1组蛋白与超螺旋DNA的相互作用是可逆的。
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