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伴有间变性少突胶质细胞成分的大脑节细胞胶质瘤

Cerebral ganglioglioma with anaplastic oligodendroglial component.

作者信息

Allegranza A, Pileri S, Frank G, Ferracini R

机构信息

Department of Neuropathology, Istituto Neurologico C. Besta, Milan, Italy.

出版信息

Histopathology. 1990 Nov;17(5):439-41. doi: 10.1111/j.1365-2559.1990.tb00765.x.

DOI:10.1111/j.1365-2559.1990.tb00765.x
PMID:1706300
Abstract

We report an unusual and possibly unique example of cerebral ganglioglioma with an anaplastic oligodendroglial component. The latter was documented on both morphological and immunohistochemical grounds. Immunohistochemically, the anaplastic cells were strongly positive with the monoclonal antibody anti-Leu-7, while they lacked glial fibrillary acid protein, vimentin and neurofilaments.

摘要

我们报告了一例罕见且可能独特的伴有间变性少突胶质细胞成分的大脑神经节胶质瘤病例。后者通过形态学和免疫组织化学方法得以证实。免疫组织化学显示,间变性细胞对单克隆抗体抗-Leu-7呈强阳性,而缺乏胶质纤维酸性蛋白、波形蛋白和神经丝。

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