Tesfaye F, Nawi N G, Van Minh H, Byass P, Berhane Y, Bonita R, Wall S
Department of Community Health, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
J Hum Hypertens. 2007 Jan;21(1):28-37. doi: 10.1038/sj.jhh.1002104. Epub 2006 Oct 26.
Despite a growing burden of obesity and hypertension in developing countries, there is limited information on the contribution of body mass index (BMI) to blood pressure (BP) in these populations. This study examines the association between BMI and BP in three populations across Africa and Asia. Data on BMI, BP and other background characteristics of study participants were generated using the World Health Organization STEPwise approach to surveillance (STEPS), at three demographic surveillance sites in Ethiopia, Vietnam and Indonesia. BMI and BP increased along the socioeconomic gradient across the three countries. Mean (s.d.) BMI in men varied between 19.41 (2.28) in Ethiopia to 21.17 (2.86) in Indonesia. A high prevalence of overweight/obesity was noted among Indonesian women (25%) and men (10%), whereas low BMI was widely prevalent in Ethiopia and Vietnam, ranging from 33 to 43%. Mean (s.d.) systolic BP (SBP) among men varied between 117.15 (15.35) in Ethiopia to 127.33 (17.80) in Indonesia. The prevalence of hypertension was highest among women (25%) and men (24%) in Indonesia. Mean BP levels increased with increasing BMI. The risk of hypertension was higher among population groups with overweight and obesity (BMI>/=25 kg/m(2)); odds ratio (95% confidence interval); 2.47 (1.42, 4.29) in Ethiopia, 2.67 (1.75, 4.08) in Vietnam and 7.64 (3.88, 15.0) in Indonesia. BMI was significantly and positively correlated with both SBP and DBP in all the three populations, correlation coefficient (r) ranging between 0.23 and 0.27, P<0.01. High BP exists in a background of undernutrition in populations at early stages of the epidemiologic transition.
尽管发展中国家肥胖和高血压的负担日益加重,但关于这些人群中体重指数(BMI)对血压(BP)影响的信息有限。本研究调查了非洲和亚洲三个地区人群中BMI与BP之间的关联。使用世界卫生组织的逐步监测方法(STEPS),在埃塞俄比亚、越南和印度尼西亚的三个人口监测点收集了研究参与者的BMI、BP及其他背景特征数据。在这三个国家中,BMI和BP均随社会经济梯度升高。男性的平均(标准差)BMI在埃塞俄比亚为19.41(2.28),在印度尼西亚为21.17(2.86)。印度尼西亚女性(25%)和男性(10%)中超重/肥胖的患病率较高,而低BMI在埃塞俄比亚和越南广泛存在,范围为33%至43%。男性的平均(标准差)收缩压(SBP)在埃塞俄比亚为117.15(15.35),在印度尼西亚为127.33(17.80)。印度尼西亚女性(25%)和男性(24%)的高血压患病率最高。平均血压水平随BMI升高而增加。超重和肥胖人群(BMI≥25 kg/m²)患高血压的风险更高;比值比(95%置信区间):埃塞俄比亚为2.47(1.42, 4.29),越南为2.67(1.75, 4.08),印度尼西亚为7.64(3.88, 15.0)。在所有三个地区人群中,BMI与SBP和DBP均呈显著正相关,相关系数(r)在0.23至0.27之间,P<0.01。在流行病学转变早期阶段的人群中,高血压在营养不良的背景下存在。