Sator P-G, Feldmann R, Wanke T, Gschnait F, Breier F
Dermatologische Abteilung, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, 1130, Wien.
Hautarzt. 2007 May;58(5):440, 442-4. doi: 10.1007/s00105-006-1226-4.
Histologically, leukocytoclastic vasculitis (LV) presents with neutrophilic granulocytes with leukocytoclasia and erythrocyte extravasation, associated with variable counts of lymphocytes, plasma cells and eosinophilic granulocytes. The association of a LV with eosinophilic granulocytes and eosinophilic pneumonia was first described by Chan et al. in 1982. Our case represents the second report in the literature of this rare disease: a 85 year old patient with LV and numerous eosinophilic granulocytes in association with intermittent blood eosinophilia and Löffler syndrome (eosinophilic pulmonary infiltrates). The recurrent episodes were treated successfully with oral corticosteroids.
组织学上,白细胞破碎性血管炎(LV)表现为伴有白细胞破碎和红细胞外渗的嗜中性粒细胞,伴有数量不等的淋巴细胞、浆细胞和嗜酸性粒细胞。1982年,Chan等人首次描述了LV与嗜酸性粒细胞及嗜酸性肺炎的关联。我们的病例是该罕见疾病文献中的第二篇报道:一名85岁患者患有LV,伴有大量嗜酸性粒细胞,同时伴有间歇性血液嗜酸性粒细胞增多和吕弗勒综合征(嗜酸性肺浸润)。复发性发作通过口服皮质类固醇成功治疗。