Bigliardi L, Sansebastiano G
Department of Public Health, Sec of Hygiene, University of Parma, Italy.
J Prev Med Hyg. 2006 Jun;47(2):56-63.
The virucidal activity of chlorine-compounds was studied using hepatitis A virus (HAV) and Poliovirus 2 and comparing the disinfectant efficiency of peracetic acid. HAV presented a higher resistance to HClO than Poliovirus did. With ClO2 the inactivation times of HAV were markedly shorter. A comparison between these data and those resulting from the kinetics with peracetic acid (PA) showed that PA is less effective than chlorine. As a preliminary to future research, the PCR-test integrated with cell-cultures was experimentally introduced for a quick evaluation of the HAV-infectiveness, with the aim of possible application in the field of disinfection and of viruses-isolation from environmental and food samples.
使用甲型肝炎病毒（HAV）和脊髓灰质炎病毒2研究了氯化合物的杀病毒活性，并比较了过氧乙酸的消毒效率。与脊髓灰质炎病毒相比，HAV对HClO的抗性更高。使用ClO2时，HAV的灭活时间明显更短。将这些数据与过氧乙酸（PA）动力学数据进行比较表明，PA的效果不如氯。作为未来研究的初步工作，实验性地引入了与细胞培养相结合的PCR检测，以快速评估HAV的感染性，目的是可能应用于消毒领域以及从环境和食品样本中分离病毒。
