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连续脑功能监测:临床实践中的最新技术水平

Continuous brain-function monitoring: state of the art in clinical practice.

作者信息

Hellström-Westas Lena, Rosén Ingmar

机构信息

Department of Paediatrics, University Hospital, SE-22185 Lund, Sweden.

出版信息

Semin Fetal Neonatal Med. 2006 Dec;11(6):503-11. doi: 10.1016/j.siny.2006.07.011. Epub 2006 Oct 24.

DOI:10.1016/j.siny.2006.07.011
PMID:17067863
Abstract

Continuous electroencephalographic (EEG) monitoring gives direct information on brain function in newborn infants needing intensive care. To improve the possibilities of long-term monitoring, the EEG is time-compressed and recorded with a reduced number of electrodes. A trend measure of the EEG, the amplitude-integrated EEG (aEEG), has proved capable of giving relevant information in newborn infants of differing levels of maturity. The electrocortical background activity gives information on the level of brain activity, which is associated with outcome in both term asphyxiated infants and in preterm infants. However, the background activity is also affected by several medications, and this must be considered when interpreting the aEEG trace. The aEEG also reveals subclinical epileptic seizure activity, and can be used for evaluation of anti-epileptic treatment. The aEEG should be used as a complement to the standard EEG, and close collaboration between neonatologists and clinical neurophysiologists is necessary for optimal performance of EEG monitoring.

摘要

连续脑电图(EEG)监测可为需要重症监护的新生儿的脑功能提供直接信息。为了提高长期监测的可能性,脑电图进行了时间压缩,并使用较少数量的电极进行记录。脑电图的一种趋势测量方法,即振幅整合脑电图(aEEG),已被证明能够为不同成熟度的新生儿提供相关信息。皮质电背景活动提供了关于脑活动水平的信息,这与足月窒息婴儿和早产儿的预后相关。然而,背景活动也受到几种药物的影响,在解释aEEG轨迹时必须考虑这一点。aEEG还可揭示亚临床癫痫发作活动,并可用于评估抗癫痫治疗。aEEG应作为标准脑电图的补充,新生儿科医生和临床神经生理学家之间的密切合作对于脑电图监测的最佳效果是必要的。

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