Dacheva V, Dimov D M, Nedialkova V, Koleva P
Vutr Boles. 1990;29(5):68-74.
The third and the fourth fraction of the complement (C3 and C4), haptoglobin, fibrinogen, alpha 1-glycoprotein, alpha 2-macroglobulin and transferrin were examined in 692 patients with inflammatory joint disease--rheumatism, rheumatoid arthritis, ankylosing spondylarthritis, psoriatic arthritis, Reiter's syndrome, sacroiliitis [correction of sacroileitis], reactive arthritis, gout, osteoarthrosis and nosologically undefined arthritis in active or nonactive phase and in 60 healthy controls. The complement fractions studied show an increase of various degree and importance in almost all groups of patients in both phases studied. The relations between the complement fractions and the other acute phase indices show significant correlations between them and the other acute phase indices. C3 and to a certain degree C4 could be added to the acute phase reacting indices. Their place in the downgrade scale is as follows: fibrinogen, haptoglobin, alpha 1-glycoprotein, C3, C4, alpha 2-macroglobulin, transferrin.
对692例患有炎症性关节疾病（包括风湿、类风湿性关节炎、强直性脊柱炎、银屑病关节炎、赖特综合征、骶髂关节炎、反应性关节炎、痛风、骨关节炎以及病因未明的关节炎）处于活动期或非活动期的患者，以及60名健康对照者，检测了补体的第三和第四成分（C3和C4）、触珠蛋白、纤维蛋白原、α1-糖蛋白、α2-巨球蛋白和转铁蛋白。在所研究的两个阶段中，几乎所有患者组中所检测的补体成分均呈现出不同程度和重要性的升高。补体成分与其他急性期指标之间的关系表明，它们与其他急性期指标之间存在显著相关性。C3以及在一定程度上C4可被归入急性期反应指标。它们在降序排列中的位置如下：纤维蛋白原、触珠蛋白、α1-糖蛋白、C3、C4、α2-巨球蛋白、转铁蛋白。
