Stojan B
Z Rheumatol. 1976 Jul-Aug;35(7-8):272-7.
The C3-Proactivator (C3-PA) and the C3 and C4 complements were determined by radio-immuno diffusion in the serum of 72 patients with definite or classical rheumatoid arthritis, 51 patients with osteoarthrosis and 42 healthy subjects. C3-PA and C4 levles were significantly higher in the serum of patients with rheumatoid arthritis than in the control group (C3-PA in 72%, C4 in 37% of the RA patients). There was also a significant difference between seropositive und seronegative cases. Elevation of both components was more frequently found in patients with seronegative rheumatoid arthritis than in the seropositive cases. However, the C3-PA serum level is not correlated with the ESR. Also an elevation of the C3-PA serum level is not specific for rheumatoid arthritis, it is also found in other inflammatory diseases as well as after surgery.
采用放射免疫扩散法测定了72例确诊或典型类风湿关节炎患者、51例骨关节炎患者及42名健康受试者血清中的C3前活化剂（C3-PA）、C3和C4补体。类风湿关节炎患者血清中的C3-PA和C4水平显著高于对照组（72%的类风湿关节炎患者C3-PA升高，37%的患者C4升高）。血清阳性和血清阴性病例之间也存在显著差异。血清阴性类风湿关节炎患者中两种成分升高的情况比血清阳性病例更常见。然而，C3-PA血清水平与血沉不相关。此外，C3-PA血清水平升高并非类风湿关节炎所特有，在其他炎症性疾病以及手术后也可发现。
