Synovial cell sarcoma of the vulva: multimodality treatment incorporating preoperative external-beam radiation, hemivulvectomy, flap reconstruction, interstitial brachytherapy, and chemotherapy.
作者信息
Holloway Caroline L, Russell Anthony H, Muto Michael, Albert Michele, Viswanathan Akila N
机构信息
Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, 75 Francis Street L2, Boston, Massachusetts, MA 02115, USA.
出版信息
Gynecol Oncol. 2007 Jan;104(1):253-6. doi: 10.1016/j.ygyno.2006.09.018. Epub 2006 Oct 30.
BACKGROUND
Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone.
CASE
We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimodality management, including preoperative intensity-modulated radiation therapy, radical hemivulvectomy, flap reconstruction, interstitial low-dose-rate brachytherapy boost, and adjuvant chemotherapy.
CONCLUSION
Based on this case and the limited data in the literature, multimodality treatment of advanced soft tissue sarcoma of the vulva may optimize local control and minimize toxicity while preserving sexual function.
Zotero 插件