Tchana-Sato Vincent, Detry Olivier, Polus Marc, Thiry Albert, Detroz Bernard, Maweja Sylvie, Hamoir Etienne, Defechereux Thierry, Coimbra Carla, De Roover Arnaud, Meurisse Michel, Honoré Pierre
Department of Abdominal Surgery and Transplantation, University of Liège, B4000, Belgium.
World J Gastroenterol. 2006 Nov 7;12(41):6699-701. doi: 10.3748/wjg.v12.i41.6699.
To report the experience of the CHU Sart Tilman, University of Liege, Belgium, in the management of appendiceal carinoid tumor.
A retrospective review of 1237 appendectomies performed in one single centre from January 2000 to May 2004, was undertaken. Analysis of demographic data, clinical presentation, histopathology, operative reports and outcome was presented.
Among the 1237 appendectomies, 5 appendiceal carcinoid tumors were identified (0.4%) in 4 male and 1 female patients, with a mean age of 29.2 years (range: 6-82 years). Acute appendicitis was the clinical presentation for all patients. Four patients underwent open appendectomy and one a laparoscopic procedure. One patient was reoperated to complete the excision of mesoappendix. All tumors were located at the tip of the appendix with a mean diameter of 0.6 cm (range: 0.3-1.0 cm). No adjuvant therapy was performed. All patients were alive and disease-free during a mean follow-up of 33 mo.
Appendiceal carcinoid tumor most often presents as appendicitis. In most cases, it is found incidentally during appendectomies and its diagnosis is rarely suspected before histological examination. Appendiceal carcinoid tumor can be managed by simple appendectomy and resection of the mesoappendix, if its size is <or=1 cm.
报告比利时列日大学 Sart Tilman 大学医院在阑尾类癌肿瘤管理方面的经验。
对 2000 年 1 月至 2004 年 5 月在单一中心进行的 1237 例阑尾切除术进行回顾性研究。分析人口统计学数据、临床表现、组织病理学、手术报告和结果。
在 1237 例阑尾切除术中，共识别出 5 例阑尾类癌肿瘤（0.4%），其中男性 4 例，女性 1 例，平均年龄 29.2 岁（范围：6 - 82 岁）。所有患者的临床表现均为急性阑尾炎。4 例患者接受了开腹阑尾切除术，1 例接受了腹腔镜手术。1 例患者再次手术以完成阑尾系膜的切除。所有肿瘤均位于阑尾尖端，平均直径 0.6 cm（范围：0.3 - 1.0 cm）。未进行辅助治疗。在平均 33 个月的随访期间，所有患者均存活且无疾病。
阑尾类癌肿瘤最常表现为阑尾炎。在大多数情况下，它是在阑尾切除术中偶然发现的，在组织学检查之前很少被怀疑。如果阑尾类癌肿瘤大小≤1 cm，可通过单纯阑尾切除术和阑尾系膜切除术进行治疗。
