Murry Thomas, Tabaee Abtin, Owczarzak Vicki, Aviv Jonathan E
Department of Otolaryngology-Head and Neck Surgery, New York Presbyterian Hospital and Columbia University College of Physicians and Surgeons, New York, New York, USA.
Ann Otol Rhinol Laryngol. 2006 Oct;115(10):754-8. doi: 10.1177/000348940611501007.
We describe the outcome of patients with cough and paradoxical vocal fold movement disorder (PVFMD) treated with respiratory retraining therapy and management of laryngopharyngeal reflux (LPR).
Twenty patients with the complaint of cough were given a diagnosis of PVFMD and treated with proton pump inhibitors for a minimum of 6 months followed by 3 to 5 sessions of respiratory retraining therapy. Pulmonary function testing (PFT) and subjective rating of cough and reflux (reflux symptom index; RSI) were performed. Also, PFT and rating of cough were performed on a group of 10 healthy volunteers with no complaint of cough.
The study group comprised 13 women and 7 men. The baseline cough rating and ratio of forced inspiratory volume at 0.5 second to forced inspiratory vital capacity (FIV0.5/FIVC) on PFT were significantly worse in the treatment group than in the control group. After therapy, 20 patients (100%) experienced improvement in cough, 19 patients (95%) experienced improvement on PFT, and 17 patients (85%) experienced improvement in the RSI score. The differences were statistically significant.
Respiratory retraining therapy combined with management of LPR is an effective treatment for patients with cough and PVFMD when a single-modality treatment is not sufficient.
我们描述了接受呼吸再训练疗法和喉咽反流(LPR)管理治疗的咳嗽伴矛盾性声带运动障碍(PVFMD)患者的治疗结果。
20例主诉咳嗽的患者被诊断为PVFMD,并接受质子泵抑制剂治疗至少6个月,随后进行3至5次呼吸再训练治疗。进行了肺功能测试(PFT)以及咳嗽和反流的主观评分(反流症状指数;RSI)。此外,对一组10名无咳嗽主诉的健康志愿者进行了PFT和咳嗽评分。
研究组包括13名女性和7名男性。治疗组的基线咳嗽评分以及PFT中0.5秒用力吸气量与用力吸气肺活量的比值(FIV0.5/FIVC)显著低于对照组。治疗后,20例患者(100%)咳嗽症状改善,19例患者(95%)PFT改善,17例患者(85%)RSI评分改善。差异具有统计学意义。
当单一治疗方式不足时,呼吸再训练疗法联合LPR管理是治疗咳嗽伴PVFMD患者的有效方法。