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利用有限元软件,基于来自外科心室修复治疗(SVRT)和心脏再同步治疗(CRT)的建模数据集,对介入前后的心脏重建数据进行量化。

Utilizing FEM-Software to quantify pre- and post-interventional cardiac reconstruction data based on modelling data sets from surgical ventricular repair therapy (SVRT) and cardiac resynchronisation therapy (CRT).

作者信息

Verhey Janko F, Nathan Nadia S

机构信息

MVIP ImagingProducts GmbH, Nörten-Hardenberg, Germany.

出版信息

Biomed Eng Online. 2006 Oct 31;5:58. doi: 10.1186/1475-925X-5-58.

DOI:10.1186/1475-925X-5-58
PMID:17076902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1636054/
Abstract

BACKGROUND

Left ventricle (LV) 3D structural data can be easily obtained using standard transesophageal echocardiography (TEE) devices but quantitative pre- and intraoperative volumetry and geometry analysis of the LV is presently not feasible in the cardiac operation room (OR). Finite element method (FEM) modelling is necessary to carry out precise and individual volume analysis and in the future will form the basis for simulation of cardiac interventions.

METHOD

A Philips/HP Sonos 5500 ultrasound device stores volume data as time-resolved 4D volume data sets. In this prospective study TomTec LV Analysis TEE Software was used for semi-automatic endocardial border detection, reconstruction, and volume-rendering of the clinical 3D echocardiographic data. With the software FemCoGen a quantification of partial volumes and surface directions of the LV was carried out for two patients data sets. One patient underwent surgical ventricular repair therapy (SVR) and the other a cardiac resynchronisation therapy (CRT).

RESULTS

For both patients a detailed volume and surface direction analysis is provided. Partial volumes as well as normal directions to the LV surface are pre- and post-interventionally compared.

CONCLUSION

The operation results for both patients are quantified. The quantification shows treatment details for both interventions (e.g. the elimination of the discontinuities for CRT intervention and the segments treated for SVR intervention). The LV quantification is feasible in the cardiac OR and it gives a detailed and immediate quantitative feedback of the quality of the intervention to the medical.

摘要

背景

使用标准经食管超声心动图(TEE)设备可轻松获取左心室(LV)的三维结构数据,但目前在心脏手术室(OR)中,对LV进行定量的术前和术中容积测定及几何分析尚不可行。有限元方法(FEM)建模对于进行精确的个体化容积分析是必要的,并且在未来将成为心脏介入模拟的基础。

方法

飞利浦/惠普Sonos 5500超声设备将容积数据存储为时间分辨的四维容积数据集。在这项前瞻性研究中,使用TomTec LV分析TEE软件对临床三维超声心动图数据进行半自动心内膜边界检测、重建和容积渲染。使用FemCoGen软件对两名患者的数据集进行LV部分容积和表面方向的量化。一名患者接受了外科心室修复治疗(SVR),另一名患者接受了心脏再同步治疗(CRT)。

结果

为两名患者均提供了详细的容积和表面方向分析。对LV表面的部分容积以及法线方向在干预前后进行了比较。

结论

对两名患者的手术结果进行了量化。量化显示了两种干预措施的治疗细节(例如,CRT干预中不连续部分的消除以及SVR干预中治疗的节段)。LV量化在心脏手术室是可行的,并且能为医疗人员提供关于干预质量的详细且即时的定量反馈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d5/1636054/4641f47a2acb/1475-925X-5-58-12.jpg
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