Talwar Nakul, Crawford Mike J, Maratos Anna, Nur Ula, McDermott Orii, Procter Simon
Department of Psychological Medicine, Claybrook Centre, St Dunstan's Road, London W6 8RP, UK.
Br J Psychiatry. 2006 Nov;189:405-9. doi: 10.1192/bjp.bp.105.015073.
Music therapy may provide a means of improving mental health among people with schizophrenia, but its effects in acute psychoses have not been explored.
To examine the feasibility of a randomised trial of music therapy for inpatients with schizophrenia, and explore its effects on mental health.
Up to 12 weeks of individual music therapy plus standard care were compared with standard care alone. Masked assessments of mental health, global functioning and satisfaction with care were conducted at 3 months.
Of 115 eligible patients 81 (70%) were randomised. Two-thirds of those randomised to music therapy attended at least four sessions (median attendance, eight sessions). Multivariate analysis demonstrated a trend towards improved symptom scores among those randomised to music therapy, especially in general symptoms of schizophrenia.
A randomised trial of music therapy for in-patients with schizophrenia is feasible. The effects and cost-effectiveness of music therapy for acute psychosis should be further explored in an explanatory randomised trial.
音乐疗法可能为改善精神分裂症患者的心理健康提供一种方法，但尚未探究其在急性精神病中的作用。
检验针对精神分裂症住院患者进行音乐疗法随机试验的可行性，并探究其对心理健康的影响。
将长达12周的个体音乐疗法加标准护理与单纯标准护理进行比较。在3个月时对心理健康、整体功能及护理满意度进行盲法评估。
115名符合条件的患者中，81名（70%）被随机分组。随机分配接受音乐疗法的患者中有三分之二至少参加了四次治疗（中位数为八次）。多变量分析表明，随机接受音乐疗法的患者症状评分有改善趋势，尤其是在精神分裂症的一般症状方面。
针对精神分裂症住院患者进行音乐疗法随机试验是可行的。应在一项解释性随机试验中进一步探究音乐疗法对急性精神病的效果和成本效益。
