Mateos I, Valencia R, Torres M J, Cantos A, Conde M, Aznar J
Servicio de Microbiologia, Hospitales Universitarios Virgen del Rocio, Sevilla, Spain.
Infect Control Hosp Epidemiol. 2006 Nov;27(11):1249-51. doi: 10.1086/508838. Epub 2006 Oct 4.
We describe an outbreak of nosocomial endophthalmitis due to a common source, which was determined to be trypan blue solution prepared in the hospital's pharmacy service. We assume that viable bacteria probably gained access to the trypan blue stock solution during cooling after autoclaving. The temporal cluster of Pseudomonas aeruginosa endophthalmitis was readily perceived on the basis of clinical and microbiological findings, and an exogenous source of contamination was unequivocally identified by means of DNA fingerprinting.
我们描述了一起因共同来源导致的医院内眼内炎暴发事件，该共同来源被确定为医院药房配制的台盼蓝溶液。我们推测，在高压灭菌后的冷却过程中，活菌可能进入了台盼蓝储备溶液。基于临床和微生物学检查结果，很容易察觉到铜绿假单胞菌性眼内炎的时间聚集性，并且通过DNA指纹图谱明确鉴定出了外源性污染来源。
