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肺误吸的管理

Management of pulmonary aspiration.

作者信息

Janda Matthias, Scheeren Thomas W L, Nöldge-Schomburg Gabriele F E

机构信息

Department of Anaesthesiology and Intensive Care Medicine, University of Rostock, Schillingallee 35, 18055 Rostock, Germany.

出版信息

Best Pract Res Clin Anaesthesiol. 2006 Sep;20(3):409-27. doi: 10.1016/j.bpa.2006.02.006.

Abstract

Pulmonary aspiration of gastric contents in the perioperative phase is associated with increased postoperative morbidity and mortality. For the management of aspiration, differentiation between acid-associated aspiration pneumonitis and aspiration pneumonia as a consequence of a secondary bacterial contamination is of crucial importance. The incidence of aspiration in elective surgery is 1 per 2000-3000 anaesthesias in adults. In children, it is slightly more common with 1 per 1200-2600 anaesthesias. In the context of emergency anaesthesias the incidence of aspiration is three to four times higher. The risk particularly increases with recent ingestion of solid food or fluids, with older patients, with pregnant women, and with consciousness-reduced patients. Besides giving a review of the pathophysiology, incidence, and the risk factors of aspiration, this article places emphasis on the practical management of this anaesthesia-associated complication. Cricoid pressure, as a non-evidence-based but clinically wide-spread method in the context of the prophylaxis of aspiration, is discussed critically. The main part deals with strategies to structure the management of aspiration by use of scientific concepts based on medical crisis management. For this, an algorithm based on current scientific investigations is presented.

摘要

围手术期胃内容物的肺误吸与术后发病率和死亡率的增加相关。对于误吸的处理,区分与酸相关的误吸性肺炎和继发细菌污染导致的吸入性肺炎至关重要。择期手术中成人误吸的发生率为每2000 - 3000例麻醉中有1例。在儿童中,发生率略高,为每1200 - 2600例麻醉中有1例。在急诊麻醉情况下,误吸的发生率高出三到四倍。风险尤其在近期摄入固体食物或液体、老年患者、孕妇以及意识降低的患者中增加。除了综述误吸的病理生理学、发生率和危险因素外,本文重点关注这种麻醉相关并发症的实际处理。环状软骨压迫作为一种在预防误吸方面虽无循证依据但临床广泛应用的方法,受到了批判性讨论。主要部分探讨了基于医疗危机管理的科学概念构建误吸处理策略的方法。为此,提出了一种基于当前科学研究的算法。

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