Laurier E, Gosset D, Hennache B, Nuttens M C, Debuire B, Lenoir L, Muller P H
Institut de Médecine Légale de médecine Sociale, Université du Droit et de la Santé, Lille.
Presse Med. 1991 Mar 9;20(9):405-8.
We studied the influence of the agonal period on the concentrations of acute phase proteins in biological fluids obtained from 26 autopsy cases. We found significant differences for C-reactive protein concentrations in serum and in pericardial fluid, between short and long agonies. The other acute phase proteins studied (alpha-1 antitrypsin, alpha-2 macroglobulin, haptoglobin) failed to show any significant difference in serum and pericardial fluid levels between the two types of agony. The increase in C-reactive protein level in the pericardial fluid is attributed to an "agonal pericarditis" which may result from an agonal myocardial necrosis. Our results could be of interest in forensic medicine.
我们研究了濒死期对从26例尸检病例获取的生物体液中急性期蛋白浓度的影响。我们发现，短濒死期和长濒死期之间，血清和心包液中C反应蛋白浓度存在显著差异。所研究的其他急性期蛋白（α-1抗胰蛋白酶、α-2巨球蛋白、触珠蛋白）在两种濒死期类型的血清和心包液水平上未显示出任何显著差异。心包液中C反应蛋白水平的升高归因于“濒死期心包炎”，这可能由濒死期心肌坏死导致。我们的结果可能在法医学上具有意义。
