Spencer James M, Kurtz Ellen S
Mount Sinai School of Medicine, New York, New York, USA.
Dermatol Surg. 2006 Nov;32(11):1353-7. doi: 10.1111/j.1524-4725.2006.32305.x.
Microdermabrasion is a popular cosmetic procedure for skin rejuvenation, which is achieved by mechanical abrasion of the skin at a superficial level.
The objective was to study the efficacy of microdermabrasion in photoaging and to investigate the compatibility of a cleanser and a lotion with microdermabrasion.
Sixteen women underwent microdermabrasion to the face once a week for a total of six treatments. Subjects were also given a personal skin care regimen (cleanser and lotion). Colorimetry values as well as investigator and patients ratings for safety and efficacy were analyzed at various time points and compared to baseline.
There were no significant changes in safety and tolerance variables throughout the study. Clinical efficacy variables (fine wrinkles, dullness, pigmentation, and large pores) significantly improved by the third treatment, with further improvement by the end of the study (six treatments). Subjects perceived improvement in facial photoaging variables. Colorimetry showed increased brightness and decreased yellowness of target skin sites on the face throughout the study.
Multiple microdermabrasions were effective in significantly improving various facial photoaging variables. The personal skin care regimen used was well tolerated by the subjects.
微晶磨皮术是一种广受欢迎的皮肤年轻化美容手术，通过在皮肤表层进行机械磨损来实现。
研究微晶磨皮术对光老化的疗效，并调查一种洁面产品和一种乳液与微晶磨皮术的兼容性。
16名女性每周对面部进行一次微晶磨皮术，共进行6次治疗。受试者还接受了个性化的皮肤护理方案（洁面产品和乳液）。在不同时间点分析比色法值以及研究者和患者对安全性和疗效的评分，并与基线进行比较。
在整个研究过程中，安全性和耐受性变量没有显著变化。临床疗效变量（细纹、暗沉、色素沉着和毛孔粗大）在第三次治疗时显著改善，在研究结束时（6次治疗）进一步改善。受试者感觉面部光老化变量有所改善。比色法显示，在整个研究过程中，面部目标皮肤部位的亮度增加，黄色度降低。
多次微晶磨皮术可有效显著改善各种面部光老化变量。受试者对所使用的个性化皮肤护理方案耐受性良好。
