Freedman Bruce M
Plastic Surgery Associates of Northern Virginia, McLean, VA, USA.
J Cosmet Dermatol. 2008 Dec;7(4):275-80. doi: 10.1111/j.1473-2165.2008.00406.x.
Hydradermabrasion is a relatively new procedure that combines crystal-free microdermabrasion with the pneumatic application of an antioxidant-based serum.
This study aims to validate the safety and efficacy of hydradermabrasion for nonablative facial rejuvenation and to determine whether antioxidant levels could be increased in the skin with this technique.
Twenty female volunteers, aged 34-56 years, were randomized into two groups. Group A underwent a series of six facial hydradermabrasion treatments using a polyphenolic antioxidant serum spaced 7-10 days apart. In Group B, the same polyphenolic antioxidant serum was applied manually to the skin for a total of six treatments at 7- to 10-day intervals. Digital photographs, skin biopsies, and skin polyphenolic antioxidant levels were obtained prior to and after the treatment regimen. Patient surveys were taken following the study.
In Group A, treated skin demonstrated increased epidermal thickness, papillary dermal thickness, and polyphenolic antioxidant levels (P < 0.01). There was replacement of elastotic dermal tissue, collagen hyalinization, and increased fibroblast density. Fine lines, pore size, and hyperpigmentation were decreased following treatment. There were no reported complications. In Group B, there was no change in skin structure, antioxidant levels, or clinical skin attributes.
Hydradermabrasion effectively improved skin quality both clinically and histologically. There were no changes to suggest that pneumatic serum application adversely affected dermal components. After hydradermabrasion, skin polyphenolic antioxidant levels were increased. In contrast, the intermittent manual application of the polyphenolic antioxidant serum without the microdermabrasion element did not result in detectable skin changes.
水合磨皮术是一种相对较新的治疗方法,它将无晶体微晶磨皮术与基于抗氧化剂的血清的气动应用相结合。
本研究旨在验证水合磨皮术用于非剥脱性面部年轻化的安全性和有效性,并确定使用该技术是否能提高皮肤中的抗氧化剂水平。
20名年龄在34 - 56岁之间的女性志愿者被随机分为两组。A组接受了一系列六次面部水合磨皮治疗,使用一种多酚抗氧化剂血清,间隔7 - 10天进行一次治疗。B组则将相同的多酚抗氧化剂血清手动涂抹于皮肤上,共进行六次治疗,间隔7至10天。在治疗方案前后获取数码照片、皮肤活检样本以及皮肤多酚抗氧化剂水平。研究结束后进行患者调查。
在A组中,治疗后的皮肤显示表皮厚度、乳头层真皮厚度和多酚抗氧化剂水平增加(P < 0.01)。弹性组织变性的真皮组织被替代,胶原透明化,成纤维细胞密度增加。治疗后细纹、毛孔大小和色素沉着均有所减少。未报告有并发症。在B组中,皮肤结构、抗氧化剂水平或临床皮肤特征均无变化。
水合磨皮术在临床和组织学上均有效改善了皮肤质量。没有变化表明气动血清应用会对真皮成分产生不利影响。水合磨皮术后,皮肤多酚抗氧化剂水平升高。相比之下,在没有微晶磨皮成分的情况下间歇性手动涂抹多酚抗氧化剂血清并未导致可检测到的皮肤变化。