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采用莫氏显微外科手术治疗的头皮肿瘤:临床特征与手术结果

Scalp tumors treated with Mohs micrographic surgery: clinical features and surgical outcome.

作者信息

Leibovitch Igal, Huilgol Shyamala C, Richards Shawn, Paver Robert, Selva Dinesh

机构信息

Oculoplastic & Orbital Division, Royal Adelaide Hospital, University of Adelaide, Adelaide, South Australia, Australia.

出版信息

Dermatol Surg. 2006 Nov;32(11):1369-74. doi: 10.1111/j.1524-4725.2006.32308.x.

Abstract

BACKGROUND

There are only a small number of reports on the outcome of scalp tumors treated with Mohs micrographic surgery (MMS).

OBJECTIVE

The objective was to present a large series of patients with scalp tumors treated with MMS in Australia between 1993 and 2002.

METHODS

This prospective, multicenter study included all patients with scalp tumors who were monitored by the Skin and Cancer Foundation Australia. The variables analyzed were patient demographics, reason for referral, preoperative tumor size and postoperative defect size, recurrences before MMS, histologic subtypes, perineural invasion, and 5-year recurrence.

RESULTS

The study included 316 patients (68% men) with a mean age of 65+/-15 years. The most common tumors were basal cell carcinoma (BCC), 57.9%; squamous cell carcinoma (SCC), 35.8%; Bowen's disease (BD), 4.1%; and atypical fibroxanthoma (AFX), 1.6%. Recurrent tumors comprised 37% of cases. The recurrence rate for 70 BCC patients who completed the 5-year follow-up was 5.7%, and for 31 SCC cases it was 3.2%. No cases of recurrence were noted in the patients with BD and AFX.

CONCLUSION

BCC was the most common scalp tumor managed by MMS. The low 5-year recurrence rate emphasizes the importance of margin controlled excision of scalp tumors.

摘要

背景

关于采用莫氏显微外科手术(MMS)治疗头皮肿瘤的结果,仅有少量报告。

目的

旨在呈现1993年至2002年间澳大利亚采用MMS治疗的大量头皮肿瘤患者情况。

方法

这项前瞻性多中心研究纳入了澳大利亚皮肤与癌症基金会监测的所有头皮肿瘤患者。分析的变量包括患者人口统计学特征、转诊原因、术前肿瘤大小和术后缺损大小、MMS术前复发情况、组织学亚型、神经周围浸润以及5年复发率。

结果

该研究纳入316例患者(68%为男性),平均年龄65±15岁。最常见的肿瘤为基底细胞癌(BCC),占57.9%;鳞状细胞癌(SCC),占35.8%;鲍温病(BD),占4.1%;非典型纤维黄色瘤(AFX),占1.6%。复发性肿瘤占病例的37%。完成5年随访的70例BCC患者的复发率为5.7%,31例SCC患者的复发率为3.2%。BD和AFX患者未出现复发病例。

结论

BCC是MMS治疗的最常见头皮肿瘤。5年低复发率强调了头皮肿瘤切缘控制切除的重要性。

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