Bossard N, Velten M, Remontet L, Belot A, Maarouf N, Bouvier A M, Guizard A V, Tretarre B, Launoy G, Colonna M, Danzon A, Molinie F, Troussard X, Bourdon-Raverdy N, Carli P M, Jaffré A, Bessaguet C, Sauleau E, Schvartz C, Arveux P, Maynadié M, Grosclaude P, Estève J, Faivre J
Hospices Civils de Lyon, Service de Biostatistique, Lyon, F-69003, France.
Eur J Cancer. 2007 Jan;43(1):149-60. doi: 10.1016/j.ejca.2006.07.021. Epub 2006 Nov 3.
We present the main results of the first population-based cancers survival study gathering all French registry data. Survival data on 205,562 cancer cases diagnosed between 01/01/1989 and 31/12/1997 were analysed. Relative survival was estimated using an excess rate model. The evolution of the excess mortality rate over the follow-up period was graphed. The analysis emphasised the effect of age at diagnosis and its variation with time after diagnosis. For breast and prostate cancers, the age-standardised five-year relative survivals were 84% and 77%, respectively. The corresponding results in men and women were 56% versus 58% for colorectal cancer and 12% versus 16% for lung cancer. For some cancer sites, the excess mortality rate decreased to low values by five years after diagnosis. For most cancer sites, age at diagnosis was a negative prognostic factor but this effect was often limited to the first year after diagnosis.
我们展示了第一项基于人群的癌症生存研究的主要结果，该研究收集了所有法国登记处的数据。分析了1989年1月1日至1997年12月31日期间确诊的205,562例癌症病例的生存数据。使用超额率模型估计相对生存率。绘制了随访期间超额死亡率的变化情况。分析强调了诊断时年龄的影响及其在诊断后随时间的变化。对于乳腺癌和前列腺癌，年龄标准化的五年相对生存率分别为84%和77%。结直肠癌在男性和女性中的相应结果分别为56%对58%，肺癌为12%对16%。对于某些癌症部位，诊断后五年超额死亡率降至低值。对于大多数癌症部位，诊断时年龄是一个负面预后因素，但这种影响通常仅限于诊断后的第一年。
