Imounga Laure Manuella, Drak Alsibai Kinan, Plenet Juliette, Wang Qiannan, Virjophe-Cenciu Beatrice, Couppie Pierre, Sabbah Nadia, Adenis Antoine, Nacher Mathieu
Registre des Cancers de Guyane (RCan Guyane), Département Research, Innovation et Santé Publique (DRISP), Cayenne Hospital Center Andrée Rosemon, 97300 Cayenne, French Guiana.
Département Formation Recherche (DFR) en Santé, Université de Guyane, 97300 Cayenne, French Guiana.
Cancers (Basel). 2023 Dec 29;16(1):178. doi: 10.3390/cancers16010178.
The objective was to review a decade of plasmacytoma (PC) and multiple myeloma (MM) data from French Guiana, and to study its spatial and temporal trends.
This was a retrospective study of MM and PC between January 2005 and December 2014 using cancer registry data, including age-standardized incidence and mortality rates.
There were 110 cases of PC and MM (62 women and 48 men), representing the eighth most frequent malignancy in French Guiana. PC and MM were much more common in females. In men, 79% of cases occurred at ≥55 years, and in women, 90% of cases occurred at ≥50 years. The median age at diagnosis was 60 years for men and 66 years for women, while it was 72 years for men and 75 years for women in mainland France. The incidence rate standardized to the world population was 5.9 patients of PC and MM per 100,000 men/year and 7.8 per 100,000 women/year.
In our territory, the incidence of PC and MM was higher and patients were diagnosed at a substantially younger age than in mainland France. Women had a greater incidence than men, and there was an increasing temporal trend of incidence among women. African ancestry and the frequency of obesity, notably among women, could have contributed to this observation.
目的是回顾法属圭亚那十年的浆细胞瘤（PC）和多发性骨髓瘤（MM）数据，并研究其空间和时间趋势。
这是一项对2005年1月至2014年12月期间的MM和PC进行的回顾性研究，使用癌症登记数据，包括年龄标准化发病率和死亡率。
共有110例PC和MM病例（62名女性和48名男性），是法属圭亚那第八大常见恶性肿瘤。PC和MM在女性中更为常见。在男性中，79%的病例发生在≥55岁，在女性中，90%的病例发生在≥50岁。男性诊断时的中位年龄为60岁，女性为66岁，而在法国本土，男性为72岁，女性为75岁。世界人口标准化发病率为每10万男性/年有5.9例PC和MM患者，每10万女性/年有7.8例。
在我们的地区，PC和MM的发病率高于法国本土，且患者诊断时的年龄要小得多。女性发病率高于男性，且女性发病率呈上升趋势。非洲血统以及肥胖的发生率，尤其是在女性中，可能导致了这一观察结果。
