Pitanupong Jarurin, Liabsuetrakul Tippawan, Vittayanont Arnont
Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
Psychiatry Res. 2007 Jan 15;149(1-3):253-9. doi: 10.1016/j.psychres.2005.12.011. Epub 2006 Nov 7.
This study aimed to validate and determine an appropriate cut-off score on the Thai Edinburgh Postnatal Depression Scale (EPDS) as a screen for postpartum depression. A prospective cohort of postpartum women at 6-8 weeks were tested using the EPDS and clinically interviewed by psychiatrists to establish a DSM-IV diagnosis of major or minor depressions in a university hospital in Southern Thailand. Of 351 postpartum women interviewed, 38 postpartum women met the criteria for depressive disorders, major depression in four women (1%) and minor depressive disorder in 34 women (10%). The area under the curve was 0.84 (95% confidence interval 0.76-0.91). Using an EPDS cut-off sum score of 6/7, major and/or minor depression was detected with a sensitivity of 74%, specificity of 74%, positive predictive value of 26% and negative predictive value of 95%. When the cut-off score was higher, the sensitivity was lower but the specificity was higher. The Thai version of the EPDS is a valid self-report instrument and is useful in Thailand where no other screening instrument for postpartum depression is available.
本研究旨在验证泰国版爱丁堡产后抑郁量表（EPDS）并确定其合适的临界分数，以作为产后抑郁的筛查工具。在泰国南部一家大学医院，对一组6 - 8周的产后女性进行前瞻性队列研究，使用EPDS对她们进行测试，并由精神科医生进行临床访谈，以依据《精神疾病诊断与统计手册》第四版（DSM-IV）确诊是否患有重度或轻度抑郁症。在接受访谈的351名产后女性中，38名符合抑郁症诊断标准，其中4名女性（1%）患有重度抑郁症，34名女性（10%）患有轻度抑郁症。曲线下面积为0.84（95%置信区间0.76 - 0.91）。使用EPDS临界总分6/7时，检测重度和/或轻度抑郁症的灵敏度为74%，特异度为74%，阳性预测值为26%，阴性预测值为95%。当临界分数提高时，灵敏度降低但特异度升高。泰国版EPDS是一种有效的自我报告工具，在泰国没有其他产后抑郁筛查工具的情况下很有用。
