Vallet-Regí María
Departamento de Química Inorgánica y Bioinorgánica, Facultad de Farmacia, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Dalton Trans. 2006 Nov 28(44):5211-20. doi: 10.1039/b610219k. Epub 2006 Oct 3.
The most significant demand for biomaterials has emerged as a consequence of the need to provide clinical treatment to a large number of patients. The search for potential solutions produces a large demand for materials suitable for bone repair or replacement. Calcium phosphates, bio-glasses, bio-glass ceramics and ordered silica mesoporous materials, among other types of materials, will be reviewed and studied from the point of view of their potential applications as replacement materials in bone repair and regeneration, as potential substrates in tissue engineering, and also as drug delivery systems. An overview on the present achievements, but also on the "missing links" will be presented.
对生物材料的最大需求是由于需要为大量患者提供临床治疗而产生的。寻找潜在解决方案引发了对适用于骨修复或替代的材料的大量需求。磷酸钙、生物玻璃、生物玻璃陶瓷和有序二氧化硅介孔材料等多种材料，将从其作为骨修复和再生替代材料的潜在应用、作为组织工程潜在基质以及作为药物递送系统的角度进行综述和研究。将对当前的成就以及“缺失环节”进行概述。
