Yildirim M Ziynet, Benli A Cağlan Karasu, Selvi Mahmut, Ozkul Ayhan, Erkoç Figen, Koçak Oner
Department of Pathology, Faculty of Veterinary Medicine, Ankara University, Dişkapi, Ankara 06110, Turkey.
Environ Toxicol. 2006 Dec;21(6):614-20. doi: 10.1002/tox.20225.
Deltamethrin, a synthetic pyrethroid contaminating aquatic ecosystems as a potential toxic pollutant, was investigated in the present study for acute toxicity. The purpose of this study was to evaluate LC(50) values of deltamethrin on Nile tilapia (Oreochromis niloticus L.) fingerlings and investigate histopathological responses of fish exposed to deltamethrin. The 48 h LC(50) value for Nile tilapia fingerlings was estimated as 4.85 microg/L using static test system. In addition, behavioral changes at each deltamethrin concentration were observed closely. All fish, exposed to 5 microg/L deltamethrin revealed severe morphological alterations in the gills and liver. In the gills hyperemia, fusion of secondary lamellae and telangiectasis were observed; whereas hydropic degenerations in liver were observed in all examined fish. The results are significant for reporting acute deltamethrin toxicity in terms of behavioral and histopathological changes: Deltamethrin is highly toxic to fingerlings.
溴氰菊酯是一种作为潜在有毒污染物污染水生生态系统的合成拟除虫菊酯，本研究对其急性毒性进行了调查。本研究的目的是评估溴氰菊酯对尼罗罗非鱼（Oreochromis niloticus L.）幼鱼的半数致死浓度（LC50）值，并研究暴露于溴氰菊酯的鱼类的组织病理学反应。使用静态试验系统，尼罗罗非鱼幼鱼的48小时LC50值估计为4.85微克/升。此外，密切观察了每个溴氰菊酯浓度下的行为变化。所有暴露于5微克/升溴氰菊酯的鱼在鳃和肝脏中都出现了严重的形态改变。在鳃中观察到充血、次生鳃小片融合和毛细血管扩张；而在所有检查的鱼中都观察到肝脏的水样变性。就行为和组织病理学变化而言，这些结果对于报告溴氰菊酯的急性毒性具有重要意义：溴氰菊酯对幼鱼具有高毒性。
