来自多尼亚纳国家公园（西班牙）野生食肉动物体内的牛分枝杆菌抗体。

Antibodies to Mycobacterium bovis in wild carnivores from Doñana National Park (Spain).

作者信息

Martín-Atance P, León-Vizcaíno L, Palomares F, Revilla E, González-Candela M, Calzada J, Cubero-Pablo M J, Delibes M

机构信息

Infectious Diseases Area, Department of Animal Health, Faculty of Veterinary Medicine, Murcia University, 30100, Murcia, Spain.

出版信息

J Wildl Dis. 2006 Jul;42(3):704-8. doi: 10.7589/0090-3558-42.3.704.

DOI:10.7589/0090-3558-42.3.704

PMID:17092907

Abstract

We conducted a retrospective serologic survey for antibodies against the MPB70 protein of Mycobacterium bovis in wild carnivores from Doñana National Park (southwestern Spain). Serum samples from 118 red foxes (Vulpes vulpes), 39 Iberian lynx (Lynx pardinus), 31 Eurasian badgers (Meles meles), five Egyptian mongoose (Herpestes ichneumon), four European genet (Genetta genetta), and one Eurasian otter (Lutra lutra) were analyzed using an indirect competitive enzyme-linked immunoassay. Antibodies against the MPB70 protein of M. bovis were detected in seven badgers, five foxes, and one lynx. The frequency of positive animals was significantly higher in badger (23%) than in lynx (3%) and fox (4%). Antibodies were not detected in other species. Annual antibody frequency peaked at 38% in badgers and 11% for red fox. These species may contribute to persistence of bovine tuberculosis in Doñana.

摘要

我们对来自多尼亚纳国家公园（西班牙西南部）的野生食肉动物进行了一项回顾性血清学调查，以检测其针对牛分枝杆菌MPB70蛋白的抗体。使用间接竞争酶联免疫分析法分析了118只赤狐（赤狐属）、39只伊比利亚猞猁（猞猁属）、31只欧亚獾（獾属）、5只埃及獴（埃及獴属）、4只欧洲鼬獾（鼬獾属）和1只欧亚水獭（水獭属）的血清样本。在7只獾、5只狐狸和1只猞猁中检测到了针对牛分枝杆菌MPB70蛋白的抗体。獾（23%）中阳性动物的频率显著高于猞猁（3%）和狐狸（4%）。在其他物种中未检测到抗体。獾的年度抗体频率峰值为38%，赤狐为11%。这些物种可能对多尼亚纳地区牛结核病的持续存在起到了作用。