Yi Feng, Lu Jian-Wei, Guo Zhao-Xia, Yu Jian
Institute of Polymer Science and Engineering, Department of Chemical Engineering, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, P R. China.
J Biomater Sci Polym Ed. 2006;17(9):1015-24. doi: 10.1163/156856206778365997.
Poly(vinyl alcohol) (PVA) has been blended with soluble eggshell membrane protein (SEP) to improve the mechanical properties of SEP film that is brittle. Tensile strength and elongation-at-break increase with increasing amount of PVA. When the SEP/PVA proportion is 1:1, a strong and flexible film is obtained, having a tensile strength of 22.7 MPa and elongation-at-break of 106%. Although scanning electron microscopy observation of the freeze-fractured cross-section shows microphase separation, interaction between SEP and PVA exists, as revealed by FT-IR. NIH3T3 cell culture demonstrates that SEP/PVA blend films with up to 50% of PVA show biocompatibility comparable to pure SEP film.
聚乙烯醇（PVA）已与可溶性蛋壳膜蛋白（SEP）共混，以改善脆性SEP膜的机械性能。拉伸强度和断裂伸长率随PVA用量的增加而提高。当SEP/PVA比例为1:1时，可得到一种强度高且柔韧的薄膜，其拉伸强度为22.7MPa，断裂伸长率为106%。尽管对冷冻断裂横截面的扫描电子显微镜观察显示存在微相分离，但傅里叶变换红外光谱表明SEP与PVA之间存在相互作用。NIH3T3细胞培养表明，PVA含量高达50%的SEP/PVA共混膜显示出与纯SEP膜相当的生物相容性。
