Starkey P M, Clover L M, Rees M C
Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington, Oxford, U.K.
Eur J Obstet Gynecol Reprod Biol. 1991 May 10;39(3):203-7. doi: 10.1016/0028-2243(91)90058-s.
Morphometric analysis and immunohistology of tissue sections have been used to assess variation, during the normal menstrual cycle, of the bone marrow-derived cell populations in human endometrium. Levels of T cells and macrophages were found to be relatively constant throughout the cycle. In contrast, numbers of large granular lymphocytes, identified as being CD56-positive, were generally low between days 10 and 19, but increased sharply in the latter part of the luteal phase, decreasing again after menstruation. This LGL population is known to be abundant in first trimester pregnancy decidua, and is presumed to play a role in early pregnancy success.
组织切片的形态计量分析和免疫组织学已被用于评估人类子宫内膜中骨髓来源细胞群在正常月经周期中的变化。发现T细胞和巨噬细胞的水平在整个周期中相对恒定。相比之下，被鉴定为CD56阳性的大颗粒淋巴细胞数量在第10天至19天之间通常较低，但在黄体期后期急剧增加，月经后又再次下降。已知这种大颗粒淋巴细胞群在妊娠早期蜕膜中丰富，并推测其在早期妊娠成功中发挥作用。
