Mizuno Junichi, Nakagawa Hiroshi
Department of Neurological Surgery, Aichi Medical University, 21 Karimata, Yazako, Nagakute, Aichi-gun, Aichi 480-1195, Japan.
Spine J. 2006 Nov-Dec;6(6 Suppl):282S-288S. doi: 10.1016/j.spinee.2006.05.009.
This study was designed to determine the management strategies and outcomes of ossification of the posterior longitudinal ligament (OPLL) of the cervical spine.
One hundred twenty-one patients with radiologically proven OPLL including early form of OPLL (EOPLL) and hypertrophy of the posterior longitudinal ligament (HPLL) underwent surgical intervention either by the anterior procedure or posterior procedure from 1993 to 2002. The anterior approach with direct removal of OPLL was performed on 111 patients with one- or two-level OPLL, whereas expansive laminoplasty was performed as the choice posterior procedure on 10 cases with extensive OPLL. The surgery-related outcome was excellent or good for 88% and fair for 12%. This clinical improvement correlated well with the severity of the preoperative myelopathy. Two patients underwent the second anterior procedure after expansive laminoplasty. OPLL associated with dural ossification may show cerebrospinal fluid leakage after resection of the OPLL and dural ossification.
One- or two-level OPLL can be resected by an anterior approach with partial corpectomy, whereas expansive laminoplasty is indicated for multilevel compressive myelopathy due to OPLL. EOPLL and HPLL should be carefully examined with radiological workups because they are a prestage form of OPLL.
本研究旨在确定颈椎后纵韧带骨化症(OPLL)的治疗策略及治疗结果。
1993年至2002年期间,121例经影像学证实为OPLL的患者,包括早期型OPLL(EOPLL)和后纵韧带肥厚(HPLL),接受了前路或后路手术干预。111例单节段或双节段OPLL患者采用直接切除OPLL的前路手术,而10例广泛OPLL患者则选择后路扩大成形术作为后路手术方式。手术相关结果优良率为88%,一般为12%。这种临床改善与术前脊髓病的严重程度密切相关。2例患者在扩大成形术后接受了二次前路手术。OPLL合并硬脊膜骨化在切除OPLL和硬脊膜骨化后可能出现脑脊液漏。
单节段或双节段OPLL可通过前路部分椎体次全切除术切除,而后路扩大成形术适用于因OPLL导致的多节段压迫性脊髓病。EOPLL和HPLL应通过影像学检查仔细评估,因为它们是OPLL的前期形式。