Lucas Sean R, Platts-Mills Thomas A E
University of Virginia Health Systems, Asthma and Allergic Diseases Center, Charlottesville, VA 22908-1355, USA.
Paediatr Respir Rev. 2006 Dec;7(4):233-8. doi: 10.1016/j.prrv.2006.08.001. Epub 2006 Oct 17.
None of the explanations proposed for the increase in paediatric asthma have been adequate. It is becoming apparent that the cause of the increase in asthma must be multi-factorial. Increasing attention has been focused on the role of lifestyle in the development of asthma. Lifestyle changes that have occurred in children are those in diet and decreased physical activity, with obesity being the product of these changes. The increase in asthma, obesity and a sedentary lifestyle have occurred together. However, a temporal relationship between asthma, obesity and decreased physical activity has not been determined in the paediatric literature. Limited data suggest that decreased physical activity could be playing a role in the aetiology of asthma independent of obesity. Furthermore, there has been substantial research on the benefits of exercise programmes for paediatric patients with asthma. Longitudinal trials monitoring physical activity, obesity and the development of asthma are needed.
对于儿童哮喘发病率上升所提出的解释都不充分。越来越明显的是，哮喘发病率上升的原因肯定是多因素的。人们越来越关注生活方式在哮喘发病过程中的作用。儿童生活方式发生的变化包括饮食方面的变化以及身体活动减少，肥胖就是这些变化的结果。哮喘发病率上升、肥胖以及久坐不动的生活方式是同时出现的。然而，儿科文献中尚未确定哮喘、肥胖和身体活动减少之间的时间关系。有限的数据表明，身体活动减少可能在哮喘病因中发挥作用，且与肥胖无关。此外，对于哮喘患儿运动计划的益处已有大量研究。需要进行监测身体活动、肥胖和哮喘发病情况的纵向试验。
