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乳糜泻的并发症:所有患者都有风险吗?

Complications of coeliac disease: are all patients at risk?

作者信息

Goddard C J R, Gillett H R

机构信息

St John's Hospital, Howden Road West, Livingston, West Lothian EH54 6PP, UK.

出版信息

Postgrad Med J. 2006 Nov;82(973):705-12. doi: 10.1136/pgmj.2006.048876.

DOI:10.1136/pgmj.2006.048876
PMID:17099088
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2660494/
Abstract

Coeliac disease is a common condition that is increasingly being recognised as a result of the development of sensitive and specific serology. The diagnosis of coeliac disease and its subsequent treatment with a gluten-free diet have implications for the patient, not just for symptom control but also for the possible effect on quality of life and risk of complications. Whether the mode of presentation of coeliac disease has an effect on survival or risk of complication is yet unclear. This article reviews the available evidence regarding these issues.

摘要

乳糜泻是一种常见疾病,由于敏感且特异的血清学检测方法的发展,其越来越多地被认识到。乳糜泻的诊断及其随后采用无麸质饮食的治疗对患者具有重要意义,不仅关乎症状控制,还涉及对生活质量的潜在影响以及并发症风险。乳糜泻的表现方式是否会对生存率或并发症风险产生影响尚不清楚。本文综述了关于这些问题的现有证据。

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本文引用的文献

1
Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphoma.乳糜泻中的恶性淋巴瘤:除肠病型T细胞淋巴瘤外其他淋巴瘤类型风险增加的证据。
Gut. 2005 Jan;54(1):54-9. doi: 10.1136/gut.2003.032094.
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Risk of malignancy in diagnosed coeliac disease: a 24-year prospective, population-based, cohort study.确诊的乳糜泻患者发生恶性肿瘤的风险:一项基于人群的24年前瞻性队列研究。
Aliment Pharmacol Ther. 2004 Oct 1;20(7):769-75. doi: 10.1111/j.1365-2036.2004.02177.x.
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Lymphoproliferative and intestinal malignancies in 214 patients with biopsy-defined celiac disease.214例经活检确诊为乳糜泻患者的淋巴增殖性疾病和肠道恶性肿瘤
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Stratification of bone fracture risk in patients with celiac disease.乳糜泻患者骨折风险的分层
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Bone mineral density in children with untreated and treated celiac disease.未经治疗和已治疗的乳糜泻患儿的骨矿物质密度
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6
Coeliac disease. II. The presence in wheat of a factor having a deleterious effect in cases of coeliac disease.乳糜泻。II. 小麦中存在对乳糜泻患者有有害作用的一种因子。
Acta Paediatr (Stockh). 1953 Jan;42(1):34-42. doi: 10.1111/j.1651-2227.1953.tb05563.x.
7
Fracture experience of patients with coeliac disease: a population based survey.乳糜泻患者的骨折经历:一项基于人群的调查。
Gut. 2003 Apr;52(4):518-22. doi: 10.1136/gut.52.4.518.
8
European and North American populations should be screened for coeliac disease.欧洲和北美人群应接受乳糜泻筛查。
Gut. 2003 Feb;52(2):170-1. doi: 10.1136/gut.52.2.170.
9
European and North American populations should be screened for coeliac disease.欧洲和北美人群应接受乳糜泻筛查。
Gut. 2003 Feb;52(2):168-9. doi: 10.1136/gut.52.2.168.
10
Fracture risk in patients with celiac Disease, Crohn's disease, and ulcerative colitis: a nationwide follow-up study of 16,416 patients in Denmark.乳糜泻、克罗恩病和溃疡性结肠炎患者的骨折风险:丹麦16416例患者的全国性随访研究
Am J Epidemiol. 2002 Jul 1;156(1):1-10. doi: 10.1093/aje/kwf007.