González J, Orero A, Prieto J
Servicio de Microbiología, Hospital Universitario de Salamanca, Facultad de Medicina, Universidad de Salamanca.
Rev Esp Quimioter. 2006 Sep;19(3):275-85.
This study aimed to determine how many antibiotics were stored in Spanish households, analyzing their origin and characteristics (number, antibiotic type and pharmaceutical form). In addition, some general characteristics of the "home medicine cabinet" were investigated. The study was conducted by telephone interviews with one of the heads of the family in 1,000 randomly chosen Spanish homes, but in accordance with a territorial distribution proportional to the Spanish population and to the urban and rural setting. According to the results obtained, there was at least one antibiotic packet in 37% of Spanish households, mostly corresponding (96.5%) to broad-spectrum semisynthetic penicillin (amoxycillin or clavulanic-amoxycillin). A total of 59.2% of the packets found corresponded to solid oral forms (tablets, capsules, etc.) and 40.4% corresponded to liquid oral forms (syrup, suspension, sachet). The antibiotics were mostly obtained by medical prescription (84.9%), self-medication being the origin in almost 15% of them. There was a member of the family under antibiotic treatment at the time of the study in only 30% of the households that had one or more containers. The financial evaluation of the "leftover" antibiotic doses makes it possible to estimate a cost of about 18 million euros, more than 12 million of which would have been financed by the Health Care Administration. The results show that storing of antibiotics continues to be important in Spain, even though a considerable decrease has been observed in the last 10 years. This could be related to a progressive abandonment of self-medicating attitudes.
本研究旨在确定西班牙家庭中储存了多少抗生素,分析其来源和特征(数量、抗生素类型和剂型)。此外,还调查了“家庭药箱”的一些一般特征。该研究通过对1000个随机选择的西班牙家庭中的一位户主进行电话访谈来进行,但访谈依据的是与西班牙人口以及城乡分布成比例的地域分布。根据所得结果,37%的西班牙家庭中至少有一包抗生素,其中大部分(96.5%)对应于广谱半合成青霉素(阿莫西林或克拉维酸 - 阿莫西林)。总共发现的药包中有59.2%对应固体口服剂型(片剂、胶囊等),40.4%对应液体口服剂型(糖浆、混悬液、药包)。抗生素大多通过医生处方获得(84.9%),约15%的抗生素来源于自我用药。在有一个或多个抗生素容器的家庭中,只有30%的家庭在研究时有家庭成员正在接受抗生素治疗。对“剩余”抗生素剂量的财务评估使得能够估计成本约为1800万欧元,其中超过1200万欧元由医疗保健管理部门提供资金。结果表明,在西班牙,抗生素的储存仍然很重要,尽管在过去10年中已观察到显著下降。这可能与自我用药态度的逐渐摒弃有关。